Biofilm formation is a key virulence factor for a wide range of microorganisms that cause
chronic infections. The multifactorial nature of biofilm development and drug tolerance …

Due to the continuous rise in biofilm‐related infections, biofilms seriously threaten human
health. The formation of biofilms makes conventional antibiotics ineffective and dampens …

In most environments, bacteria reside primarily in biofilms, which are social consortia of cells
that are embedded in an extracellular matrix and undergo developmental programmes …

Biofilms are aggregate of microorganisms in which cells are frequently embedded within a
self-produced matrix of extracellular polymeric substance (EPS) and adhere to each other …

The airways of patients with cystic fibrosis are colonized with diverse bacterial communities
that change dynamically during pediatric years and early adulthood. Staphylococcus aureus …

Iron is one of the major limiting factors and essential nutrients of microbial life. Since in
nature it is not readily available in the preferred form, microorganisms produce small high …

Pulmonary drug delivery is a highly attractive topic for the treatment of infectious lung
diseases. Drug delivery via the pulmonary route offers unique advantages of no first-pass …

Pseudomonas aeruginosa is a leading cause of hospital-acquired pneumonia and chronic
lung infections in cystic fibrosis patients. Iron is essential for bacterial growth, and P …

Pseudomonas aeruginosa (PA) uses several virulence factors to establish chronic
respiratory infections in bronchiectasis, chronic obstructive pulmonary disease, and cystic …

The opportunistic pathogen Pseudomonas aeruginosa forms biofilms, which render it more
resistant to antimicrobial agents. Levels of iron in excess of what is required for planktonic …