Pyroptosis is a form of cell death mediated by gasdermin D (GSDMD); it is characterised by
NLRP3 inflammasome activation, caspase activation, cell membrane pore formation, and …

Intervertebral disc degeneration (IDD) serves as an independent risk factor for lower back
pain and is closely associated with spinal musculoskeletal disorders, including lumbar disc …

Background Pyroptosis is closely related to inflammation. However, the molecular
mechanisms and pathologic contributions of pyroptotic epithelial cell are not yet fully …

It is widely accepted that narcotic use during pregnancy and specific environmental factors
(eg, maternal immune activation and chronic stress) may increase risk of neuropsychiatric …

Cancer cells possess an extraordinary ability to dodge cell death through various pathways,
granting them a form of immortality—a key obstacle in oncotherapy. Thus, it's vital to unravel …

Tissues have remarkable natural capabilities to regenerate for the purpose of physiological
turnover and repair of damage. Adult mesenchymal stem cells (MSCs) are well known for …

Mesenchymal stem cell (MSC) is a potential therapeutic material that has self-renewal,
multilineage differentiation, and immunomodulation properties. However, the biological …

Mevastatin (HMG-CoA reductase inhibitor) isolated from Penicillium citrinum is known to the
first statin that inhibitor of cholesterol synthesis. Recently, several clinical reports of other …

Abstract γδ T cells located near the epithelial barrier are integral components of local
inflammatory and innate immune responses. We have previously reported the presence of …

Background. Diabetic keratopathy (DK) poses a significant challenge in diabetes mellitus,
yet its molecular pathways and effective treatments remain elusive. The aim of our research …