Sepsis-associated acute kidney injury (SA-AKI) is common in critically ill patients and is
strongly associated with adverse outcomes, including an increased risk of chronic kidney …

In patients with acute circulatory failure, the decision to give fluids or not should not be taken
lightly. The risk of overzealous fluid administration has been clearly established. Moreover …

Objective To provide an update to “Surviving Sepsis Campaign Guidelines for Management
of Sepsis and Septic Shock: 2012”. Design A consensus committee of 55 international …

Objective: To determine the impact of renal biomarker–guided implementation of the Kidney
Disease Improving Global Outcomes (KDIGO) care bundle on the incidence of acute kidney …

Importance Fluid overload occurring as a consequence of overly aggressive fluid
resuscitation may adversely affect outcome in hemodynamically unstable critically ill …

Over the last decade, the way to monitor hemodynamics at the bedside has evolved
considerably in the intensive care unit as well as in the operating room. The most important …

The central venous pressure (CVP) is the most frequently used variable to guide fluid
resuscitation in critically ill patients, although its use has been challenged. In this viewpoint …

Correction of intravascular hypovolemia is a key component of the prevention and
management of acute kidney injury (AKI), but excessive fluid administration is associated …

Background Fluid responsiveness is a crucial concept in the management of critically ill
patients, guiding fluid resuscitation to optimize hemodynamics while avoiding fluid overload …

Background Current recommendations support guiding fluid resuscitation through the
assessment of fluid responsiveness. Recently, the concept of fluid tolerance and the …