The Role of Diet in Parkinson's Disease

KN Tosefsky, J Zhu, YN Wang, JST Lam… - Journal of …, 2024 - content.iospress.com
The aim of this review is to examine the intersection of Parkinson's disease (PD) with
nutrition, to identify best nutritional practices based on current evidence, and to identify gaps …

Epidemiology of Parkinson's Disease: An Update

JR Deliz, CM Tanner, P Gonzalez-Latapi - Current neurology and …, 2024 - Springer
Epidemiology of Parkinson’s Disease: An Update | Current Neurology and Neuroscience
Reports Skip to main content SpringerLink Account Menu Find a journal Publish with us Track …

Risk factors associated with age at onset of Parkinson's disease in the UK Biobank

Y Huang, Q Chen, Z Wang, Y Wang, A Lian… - npj Parkinson's …, 2024 - nature.com
Substantial evidence shown that the age at onset (AAO) of Parkinson's disease (PD) is a
major determinant of clinical heterogeneity. However, the mechanisms underlying …

Lifestyle factors and clinical severity of Parkinson's disease

C Gabbert, IR König, T Lüth, M Kasten, A Grünewald… - Scientific Reports, 2023 - nature.com
Genetic factors, environmental factors, and gene–environment interactions have been found
to modify PD risk, age at onset (AAO), and disease progression. The objective of this study …

Interaction between Caffeine Consumption & Genetic susceptibility in Parkinson's disease: A systematic review

Y Yang, ZD Zhou, LX Yi, BJW Tan, EK Tan - Ageing Research Reviews, 2024 - Elsevier
Background Caffeine is one of the most consumed psychoactive substances globally.
Caffeine-gene interactions in Parkinson's disease (PD) has not been systematically …

Update to the treatment of Parkinson's disease based on the gut-brain axis mechanism

X Sun, L Xue, Z Wang, A Xie - Frontiers in neuroscience, 2022 - frontiersin.org
Gastrointestinal (GI) symptoms represented by constipation were significant non-motor
symptoms of Parkinson's disease (PD) and were considered early manifestations and …

Fox Insight at 5 years-a cohort of 54,000 participants contributing longitudinal patient-reported outcome, genetic, and microbiome data relating to Parkinson's disease

J Gottesman, Y Karim, J Forbes, L Kirsch, K Stagman… - Scientific Data, 2024 - nature.com
Fox Insight is an online, longitudinal study of over 54,000 people with and without
Parkinson's disease, facilitating discovery, validation, and reproducibility in Parkinson's …

Non-steroidal anti-inflammatory drug use and markers of Parkinson's disease progression: A retrospective cohort study

G Kuhlman, P Auinger, S Duff-Canning, A Lang… - Journal of the …, 2023 - Elsevier
Background Previous studies demonstrated reduced incidence of Parkinson's disease (PD)
with regular non-steroidal anti-inflammatory drug (NSAID) exposure, particularly ibuprofen …

Interaction of Mitochondrial Polygenic Score and Lifestyle Factors in LRRK2 p. Gly2019Ser Parkinsonism

T Lüth, C Gabbert, S Koch, IR König… - Movement …, 2023 - Wiley Online Library
Background A mitochondrial polygenic score (MGS) is composed of genes related to
mitochondrial function and found to be associated with Parkinson's disease (PD) risk …

A computational framework for predicting novel drug indications using graph convolutional network with contrastive learning

Y Luo, W Shan, L Peng, L Luo, P Ding… - IEEE Journal of …, 2024 - ieeexplore.ieee.org
Inferring potential drug indications plays a vital role in the drug discovery process. It can be
time-consuming and costly to discover novel drug indications through biological …