Arsenic is a hazardous heavy metalloid that imposes threats to human health globally. It is
widely spread throughout the environment in various forms. Arsenic-based compounds are …

Inorganic arsenic (iAs) is a natural toxicant which, upon entering the biosphere, undergoes
extensive biotransformation and becomes a portal for generating various organic …

Arsenic trioxide (ATO) is a highly toxic arsenical which has been successfully exploited for
treating acute promyelocytic leukemia (APL). Unfortunately, its therapeutic efficacy is …

The detoxification of quinones through NAD (P) H: quinone oxidoreductase (NQO1) is a
crucial mechanism to maintain cellular homeostasis. The exposure to heavy metals …

The aryl hydrocarbon receptor (AhR) functions as a vital ligand-activated transcription factor,
governing both physiological and pathophysiological processes. Notably, it responds to …

Abstract Methylmercury (MeHg) and 2, 3, 7, 8-tetrachlorodibenzodioxin (TCDD) are potent
environmental pollutants implicated in the modulation of xenobiotic-metabolizing enzymes …

The mangrove fish (Oryzias curvinotus) serves as a model for researching environmental
adaptation and sexual development. To further such research, we sequenced and …

Ponatinib and tofacitinib, established kinase inhibitors and FDA-approved for chronic
myeloid leukemia and rheumatoid arthritis, are recently undergoing investigation in diverse …

The human aryl hydrocarbon receptor (AhR), a ligand‐dependent transcription factor, plays
a pivotal role in a diverse array of pathways in biological and pathophysiological events …