Modeling and simulation of ion channels

C Maffeo, S Bhattacharya, J Yoo, D Wells… - Chemical …, 2012 - ACS Publications
Transport of ions through pores in membranes is a process of fundamental importance to
cell biology. In living organisms, such transport is facilitated by ion channels that utilize the …

Electrodiffusion phenomena in neuroscience and the nernst–planck–poisson equations

JJ Jasielec - Electrochem, 2021 - mdpi.com
This work is aimed to give an electrochemical insight into the ionic transport phenomena in
the cellular environment of organized brain tissue. The Nernst–Planck–Poisson (NPP) …

Ion concentration polarization in polyelectrolyte-modified nanopores

LH Yeh, M Zhang, S Qian, JP Hsu… - The Journal of Physical …, 2012 - ACS Publications
Nanopores functionalized with synthetic or biological polyelectrolyte (PE) brushes have
significant potentials to rectify ionic current and probe single biomacromolecules. In this …

Sensing the performance of artificially intelligent nanopores developed by integrating solid-state nanopores with machine learning methods

M Taniguchi, H Takei, K Tomiyasu… - The Journal of …, 2022 - ACS Publications
Solid-state nanopores with a through-hole diameter of less than a few hundred nanometers
can detect single nanoparticles owing to the ionic current flowing through the nanopore …

Roughness effects on the surface charge properties of silica nanoparticles

BO Alan, M Barisik, HG Ozcelik - The Journal of Physical …, 2020 - ACS Publications
The surface charge property of silica nanoparticles plays a key role in their function.
Previous studies assumed surface charge as a homogeneously distributed constant material …

The design and characterization of multifunctional aptamer nanopore sensors

L Mayne, CY Lin, SDR Christie, ZS Siwy, M Platt - ACS nano, 2018 - ACS Publications
Aptamer-modified nanomaterials provide a simple, yet powerful sensing platform when
combined with resistive pulse sensing technologies. Aptamers adopt a more stable tertiary …

Angular‐Inertia Regulated Stable and Nanoscale Sensing of Single Molecules Using Nanopore‐In‐A‐Tube

J Yang, T Pan, T Liu, C Mao, HP Ho… - Advanced …, 2025 - Wiley Online Library
Nanopore is commonly used for high‐resolution, label‐free sensing, and analysis of single
molecules. However, controlling the speed and trajectory of molecular translocation in …

Regulating current rectification and nanoparticle transport through a salt gradient in bipolar nanopores

CY Lin, LH Yeh, JP Hsu, S Tseng - Small, 2015 - Wiley Online Library
Tuning of ion and nanoparticle transport is validated through applying a salt gradient in two
types of nanopores: the inner wall of a nanopore has bipolar charges and its outer wall …

Electrokinetic ion and fluid transport in nanopores functionalized by polyelectrolyte brushes

LH Yeh, M Zhang, N Hu, SW Joo, S Qian, JP Hsu - Nanoscale, 2012 - pubs.rsc.org
Chemically functionalized nanopores in solid-state membranes have recently emerged as
versatile tools for regulating ion transport and sensing single biomolecules. This study …

Controlling pH-regulated bionanoparticles translocation through nanopores with polyelectrolyte brushes

LH Yeh, M Zhang, SW Joo, S Qian, JP Hsu - Analytical chemistry, 2012 - ACS Publications
A novel polyelectrolyte (PE)-modified nanopore, comprising a solid-state nanopore
functionalized by a nonregulated PE brush layer connecting two large reservoirs, is …