The Wnt/beta-catenin pathway is a family of proteins that is implicated in many vital cellular
functions such as stem cell regeneration and organogenesis. Several intra-cellular signal …

The prognosis for patients with biliary tract cancers (cholangiocarcinoma and gallbladder
cancer) is poor, while the incidence of these cancers is increasing. Most patients are …

Biliary tract cancers (BTC), including cholangiocarcinoma and gallbladder cancer, are poor-
prognosis and low-incidence cancers, although the incidence of intrahepatic …

WNT/β-catenin signaling is involved in many physiological processes. Its implication in
embryonic development, cell migration, and polarization has been shown. Nevertheless …

Developmental signaling pathways control a vast array of biological processes during
embryogenesis and in adult life. The WNT pathway was discovered simultaneously in …

Colorectal cancer (CRC) is a highly heterogeneous disease, for which prognosis has been
relegated to clinicopathologic staging for decades. There is a need to stratify subpopulations …

The Wnt signaling pathway plays important roles in embryonic development, homeostatic
processes, cell differentiation, cell polarity, cell proliferation, and cell migration via the β …

Colorectal cancer is a multifaceted disease which is therapeutically challenging. Based on
insights gleaned from almost a quarter century of research, it is obvious that deregulation of …

Aberrant activation of the Wnt/β-catenin pathway is frequently found in various cancers, often
through mutations of downstream components. Inhibiting β-catenin signaling in tumors with …

Wnt signalling is involved in multiple aspects of embryonic development and adult tissue
homeostasis, notably via controlling cellular proliferation and differentiation. Wnt signalling …