Molecular genetics of endometrial carcinoma

DW Bell, LH Ellenson - Annual Review of Pathology …, 2019 - annualreviews.org
Endometrial cancer is the most commonly diagnosed gynecologic malignancy in the United
States. Endometrioid endometrial carcinomas constitute approximately 85% of newly …

[HTML][HTML] Theories of endometrial carcinogenesis: a multidisciplinary approach

ME Sherman - Modern Pathology, 2000 - Elsevier
Historical observations have suggested that endometrial carcinomas vary in histopathologic
appearance and clinical features. More recent, systematic studies have provided …

The genetic landscape of endometrial clear cell carcinomas

DF DeLair, KA Burke, P Selenica, RS Lim… - The Journal of …, 2017 - Wiley Online Library
Clear cell carcinoma of the endometrium is a rare type of endometrial cancer that is
generally associated with an aggressive clinical behaviour. Here, we sought to define the …

High-grade endometrial carcinomas: morphologic and immunohistochemical features, diagnostic challenges and recommendations

R Murali, B Davidson, O Fadare… - International Journal …, 2019 - journals.lww.com
This review of challenging diagnostic issues concerning high-grade endometrial carcinomas
is derived from the authors' review of the literature followed by discussions at the …

The roles of insulin‐like growth factor 2 mRNA‐binding protein 2 in cancer and cancer stem cells

J Cao, Q Mu, H Huang - Stem cells international, 2018 - Wiley Online Library
RNA‐binding proteins (RBPs) mediate the localization, stability, and translation of the target
transcripts and fine‐tune the physiological functions of the proteins encoded. The insulin …

Emerging therapeutic targets in endometrial cancer

KJ Dedes, D Wetterskog, A Ashworth… - Nature reviews Clinical …, 2011 - nature.com
Endometrial cancer comprises a heterogeneous group of tumors, with distinct risk factors,
clinical presentation, histopathological features and molecular characteristics. Currently …

Molecular genetic pathways in various types of endometrial carcinoma: from a phenotypical to a molecular-based classification

SF Lax - Virchows Archiv, 2004 - Springer
Two types of endometrial carcinoma are distinguished with respect to biology and clinical
course. Type-I carcinoma is related to hyperestrogenism by association with endometrial …

Prognostic parameters of endometrial carcinoma

J Prat - Human pathology, 2004 - Elsevier
Endometrial carcinoma is the most common malignant tumor of the female genital tract in the
Western world. Approximately 80% of cases are well-to moderately differentiated …

Gene expression profiles of serous, endometrioid, and clear cell subtypes of ovarian and endometrial cancer

KK Zorn, T Bonome, L Gangi, GVR Chandramouli… - Clinical Cancer …, 2005 - AACR
Purpose: The presence of similar histologic subtypes of epithelial ovarian and endometrial
cancers has long been noted, although the relevance of this finding to pathogenesis and …

Current approaches to the management of patients with endometrial cancer

E Kalampokas, G Giannis, T Kalampokas… - Cancers, 2022 - mdpi.com
Simple Summary New data, the development of new methods of treatment and management
and the rising incidence of endometrial cancer require constant reviewing, in order to inform …