A current perspective on snake venom composition and constituent protein families
T Tasoulis, GK Isbister - Archives of toxicology, 2023 - Springer
Snake venoms are heterogeneous mixtures of proteins and peptides used for prey
subjugation. With modern proteomics there has been a rapid expansion in our knowledge of …
subjugation. With modern proteomics there has been a rapid expansion in our knowledge of …
Snake venomics: fundamentals, recent updates, and a look to the next decade
CH Tan - Toxins, 2022 - mdpi.com
Venomic research, powered by techniques adapted from proteomics, transcriptomics, and
genomics, seeks to unravel the diversity and complexity of venom through which knowledge …
genomics, seeks to unravel the diversity and complexity of venom through which knowledge …
Discovery and optimization of a broadly-neutralizing human monoclonal antibody against long-chain α-neurotoxins from snakes
Snakebite envenoming continues to claim many lives across the globe, necessitating the
development of improved therapies. To this end, broadly-neutralizing human monoclonal …
development of improved therapies. To this end, broadly-neutralizing human monoclonal …
[PDF][PDF] Innovative approaches to neutralizing cobra venom: Advances in antivenomics and recombinant antivenoms
I Karunarathna, K De Alvis, P Gunasena… - 2024 - researchgate.net
The King Cobra (Ophiophagus hannah) holds cultural significance and is one of the most
medically important venomous snakes worldwide. Envenomation by King Cobras often …
medically important venomous snakes worldwide. Envenomation by King Cobras often …
Convergent evolution of pain-inducing defensive venom components in spitting cobras
Convergent evolution provides insights into the selective drivers underlying evolutionary
change. Snake venoms, with a direct genetic basis and clearly defined functional …
change. Snake venoms, with a direct genetic basis and clearly defined functional …
Minor snake venom proteins: Structure, function and potential applications
Snake venoms present a great diversity of pharmacologically active compounds that may be
applied as research and biotechnological tools, as well as in drug development and …
applied as research and biotechnological tools, as well as in drug development and …
Functional proteomic analyses of Bothrops atrox venom reveals phenotypes associated with habitat variation in the Amazon
LF Sousa, JA Portes-Junior, CA Nicolau… - Journal of …, 2017 - Elsevier
Venom variability is commonly reported for venomous snakes including Bothrops atrox.
Here, we compared the composition of venoms from B. atrox snakes collected at Amazonian …
Here, we compared the composition of venoms from B. atrox snakes collected at Amazonian …
How the cobra got its flesh-eating venom: Cytotoxicity as a defensive innovation and its co-evolution with hooding, aposematic marking, and spitting
The cytotoxicity of the venom of 25 species of Old World elapid snake was tested and
compared with the morphological and behavioural adaptations of hooding and spitting. We …
compared with the morphological and behavioural adaptations of hooding and spitting. We …
Venomics of Naja sputatrix, the Javan spitting cobra: A short neurotoxin-driven venom needing improved antivenom neutralization
The venom proteome of Naja sputatrix (Javan spitting cobra) was elucidated through
reverse-phase HPLC, nano-ESI-LCMS/MS and data mining. A total of 97 distinct protein …
reverse-phase HPLC, nano-ESI-LCMS/MS and data mining. A total of 97 distinct protein …
Venomics of Bungarus caeruleus (Indian krait): Comparable venom profiles, variable immunoreactivities among specimens from Sri Lanka, India and Pakistan
AMF Oh, CH Tan, GC Ariaranee, N Quraishi… - Journal of proteomics, 2017 - Elsevier
Abstract The Indian krait (Bungarus caeruleus) is one of the “Big Four” venomous snakes
widely distributed in South Asia. The present venomic study reveals that its venom (Sri …
widely distributed in South Asia. The present venomic study reveals that its venom (Sri …