Thiophene-based derivatives as anticancer agents: An overview on decade's work

S Pathania, PA Chawla - Bioorganic Chemistry, 2020 - Elsevier
Heterocyclic compounds hold a pivotal place in medicinal chemistry due to their wide range
of biological activities and thus, are exhaustively explored in the field of drug design and …

Novel pyrimidine-bichalcophene derivatives as corrosion inhibitors for copper in 1 M nitric acid solution

MA Khaled, MA Ismail, AA El-Hossiany, AEAS Fouda - RSC advances, 2021 - pubs.rsc.org
This study targets the investigation of three pyrimidine-bichalcophene derivatives (MA-1230,
MA-1231, MA-1232) for the prevention of corrosion on copper in 1 M HNO3 via weight loss …

Thiophene and its analogs as prospective antioxidant agents: A retrospective study

R Mishra, N Kumar, N Sachan - Mini Reviews in Medicinal …, 2022 - ingentaconnect.com
The field of Free Radical Chemistry has gained considerable interest in the current scenario.
The formation of free radicals is attributable to different physiochemical factors, radiation …

Triaryl dicationic DNA minor-groove binders with antioxidant activity display cytotoxicity and induce apoptosis in breast cancer

MS Nafie, K Arafa, NK Sedky, AA Alakhdar… - Chemico-biological …, 2020 - Elsevier
Despite advances in cancer treatment modalities, DNA still stands as one of the targets for
anticancer agents. DNA minor groove binders (MGBs) represent an important investigational …

Evaluation of 4-amidinophenyl-2, 2′-bithiophene and its aza-analogue as novel corrosion inhibitors for CS in acidic media: experimental and theoretical study

AS Fouda, MA Ismail, GY El-Ewady… - Journal of Molecular …, 2017 - Elsevier
Abstract Bichalcophene series namely 4-(2, 2′-bithiophene-5-yl) benzamidine (MA-0944)
and 6-(2, 2′-bithiophene-5-yl) nicotinamidine (MA-0949) were evaluated as corrosion …

Experimental and theoretical studies on corrosion inhibition of 4-amidinophenyl-2, 2′-bifuran and its analogues in acidic media

AS Fouda, MA Ismail, AS Abousalem, GY Elewady - Rsc Advances, 2017 - pubs.rsc.org
Corrosion inhibition studies of carbon steel (CS) in 1 M HCl by newly synthesized
bichalcophene compounds namely; 4-(2, 2′-bifuran-5-yl) benzamidine (MA-0947) and 6 …

Comprehensive investigations on the action of cationic terthiophene and bithiophene as corrosion inhibitors: experimental and theoretical studies

AS Fouda, MA Ismail, AM Temraz… - New Journal of …, 2019 - pubs.rsc.org
In the present work, the inhibitive action of cationic terthiophene, namely,[2, 2′: 5′, 2′′-
terthiophene]-5-amidine (MA-1112), was compared with those of three bithiophene isosteres …

A complementary experimental and in silico studies on the action of fluorophenyl‑2, 2′‑bichalcophenes as ecofriendly corrosion inhibitors and biocide agents

AS Abousalem, MA Ismail, AS Fouda - Journal of Molecular Liquids, 2019 - Elsevier
The inhibition effect of fluorophenyl‑2, 2′‑bichalcophenes on corrosion of carbon steel (C-
steel) in 1.0 M hydrochloric acid (HCl) was investigated using various experimental …

New bithiophene derivative attenuated Alzheimer's disease induced by aluminum in a rat model via antioxidant activity and restoration of neuronal and synaptic …

K AbdEl-Raouf, HSH Farrag, R Rashed… - Journal of Trace …, 2024 - Elsevier
Background One of the hypotheses that leads to an increased incidence of Alzheimer's
disease (AD) is the accumulation of aluminum in the brain's frontal cortex. The present study …

Azafuramidines as potential anticancer Agents: Pro-apoptotic profile and cell cycle arrest

SM Elsibaei, A Amleh, MA Ismail… - Bioorganic & Medicinal …, 2024 - Elsevier
The current study aimed to test the antiproliferative activity of three azafuramidines (X, Y, and
Z) against three different human cell lines; liver HepG2, breast MCF-7, and bone U2OS. And …