Integrins are considered the main cell-adhesion transmembrane receptors that play
multifaceted roles as extracellular matrix (ECM)-cytoskeletal linkers and transducers in …

The transcription factor NF-κB is a central mediator of inflammation with multiple links to
thrombotic processes. In this review, we focus on the role of NF-κB signaling in cell types …

BACKGROUND: Obesity-induced hyperglycemia is a significant risk factor for stroke. Integrin
α9β1 is expressed on neutrophils and stabilizes adhesion to the endothelium via ligands …

The role and the mechanisms by which β1 integrins regulate the survival and
chemoresistance of T cell acute lymphoblastic leukemia (T-ALL) still are poorly addressed …

Evidence shows that tumor cells abundantly produce and release extracellular vesicles
(EVs) that can interact with stromal cells and modulate their functions. In the tumor …

Integrins are a group of heterodimers consisting of α and β subunits that mediate a variety of
physiological activities of immune cells, including cell migration, adhesion, proliferation …

Venoms are products of specialized glands and serve many living organisms to immobilize
and kill prey, start digestive processes and act as a defense mechanism. Venoms affect …

Anoikis is apoptosis initiated upon cell detachment from the native extracellular matrix. Since
survival upon detachment from basement membrane is required for metastasis, the ability to …

Integrins, which consist of two non-covalently linked α and β subunits, play a crucial role in
cell–cell adhesion and cell-extracellular matrix (ECM) interactions. Among them, integrin β1 …

Cell migration is a key process for the defense of pluricellular organisms against pathogens,
and it involves a set of surface receptors acting in an ordered fashion to contribute …