“The first thousand days” define a fetal/neonatal neurology program

MS Scher - Frontiers in Pediatrics, 2021 - frontiersin.org
Gene–environment interactions begin at conception to influence maternal/placental/fetal
triads, neonates, and children with short-and long-term effects on brain development. Life …

Neurological and developmental outcomes following neonatal encephalopathy treated with therapeutic hypothermia

N Marlow, S Shankaran, EE Rogers, NL Maitre… - Seminars in Fetal and …, 2021 - Elsevier
In randomized trials, therapeutic hypothermia (TH) is associated with reduced prevalence of
the composite outcome mortality or neurodevelopmental morbidity in infants with neonatal …

Regional variability in therapeutic hypothermia eligibility criteria for neonatal hypoxic-ischemic encephalopathy

J Proietti, GB Boylan, BH Walsh - Pediatric Research, 2024 - nature.com
Early induced therapeutic hypothermia represents the cornerstone treatment in neonates
with probable hypoxic-ischemic encephalopathy. The selection of patients for treatment …

Challenges in developing therapeutic strategies for mild neonatal encephalopathy

A McDouall, G Wassink, L Bennet… - Neural regeneration …, 2022 - journals.lww.com
There is increasing evidence that infants with mild neonatal encephalopathy (NE) have
significant risks of mortality, brain injury and adverse neurodevelopmental outcomes. In the …

[HTML][HTML] Interdisciplinary fetal-neonatal neurology training improves brain health across the lifespan

MS Scher - Frontiers in Neurology, 2024 - frontiersin.org
Integrated fetal, neonatal, and pediatric training constitutes an interdisciplinary fetal-
neonatal neurology (FNN) program. A dynamic neural exposome concept strengthens …

Short‐term morbidity and types of intrapartum hypoxia in the newborn with metabolic acidaemia: a retrospective cohort study

E di Pasquo, A Commare, B Masturzo… - … Journal of Obstetrics …, 2022 - Wiley Online Library
Objectives To assess labour characteristics in relation to the occurrence of Composite
Adverse neonatal Outcome (CAO) within a cohort of fetuses with metabolic acidaemia …

[HTML][HTML] Wavelet-based neurovascular coupling can predict brain abnormalities in neonatal encephalopathy

Y Das, RL Leon, H Liu, S Kota, Y Liu, X Wang… - NeuroImage: Clinical, 2021 - Elsevier
Background Hypoxic-ischemic encephalopathy (HIE) is a leading cause of morbidity and
mortality in neonates, but quantitative methods to predict outcomes early in their course of …

EEG phase-amplitude coupling to stratify encephalopathy severity in the developing brain

X Wang, H Liu, S Kota, Y Das, Y Liu, R Zhang… - Computer Methods and …, 2022 - Elsevier
Background Neonatal hypoxic ischemic encephalopathy (HIE) is difficult to classify within
the narrow therapeutic window of hypothermia. Neurophysiological biomarkers are needed …

Prognostic neurobiomarkers in neonatal encephalopathy

G Wassink, S Harrison, S Dhillon, L Bennet… - Developmental …, 2022 - karger.com
Therapeutic hypothermia (TH) is now a standard treatment for infants with moderate-to-
severe neonatal encephalopathy (NE), and improves brain damage on neuroimaging and …

Development, reliability, and testing of a new rating scale for neonatal encephalopathy

A Garcia-Alix, J Arnaez, G Arca, T Agut, A Alarcon… - The Journal of …, 2021 - Elsevier
Objective To develop and test the Neonatal Encephalopathy–Rating Scale (NE-RS), a new
rating scale to grade the severity of neonatal encephalopathy (NE) within the first 6 hours …