Revealing neuronal function through microelectrode array recordings

MEJ Obien, K Deligkaris, T Bullmann… - Frontiers in …, 2015 - frontiersin.org
Microelectrode arrays and microprobes have been widely utilized to measure neuronal
activity, both in vitro and in vivo. The key advantage is the capability to record and stimulate …

[HTML][HTML] The technology, opportunities and challenges of synthetic biological intelligence

BJ Kagan, C Gyngell, T Lysaght, VM Cole… - Biotechnology …, 2023 - Elsevier
Integrating neural cultures developed through synthetic biology methods with digital
computing has enabled the early development of Synthetic Biological Intelligence (SBI) …

Visualization of cortical, subcortical and deep brain neural circuit dynamics during naturalistic mammalian behavior with head-mounted microscopes and chronically …

SL Resendez, JH Jennings, RL Ung… - Nature protocols, 2016 - nature.com
Genetically encoded calcium indicators for visualizing dynamic cellular activity have greatly
expanded our understanding of the brain. However, owing to the light-scattering properties …

Tools for probing local circuits: high-density silicon probes combined with optogenetics

G Buzsáki, E Stark, A Berényi, D Khodagholy… - Neuron, 2015 - cell.com
To understand how function arises from the interactions between neurons, it is necessary to
use methods that allow the monitoring of brain activity at the single-neuron, single-spike …

High-resolution CMOS MEA platform to study neurons at subcellular, cellular, and network levels

J Müller, M Ballini, P Livi, Y Chen, M Radivojevic… - Lab on a Chip, 2015 - pubs.rsc.org
Studies on information processing and learning properties of neuronal networks would
benefit from simultaneous and parallel access to the activity of a large fraction of all neurons …

Recent trends in microelectrode array technology for in vitro neural interface platform

R Kim, S Joo, H Jung, N Hong, Y Nam - Biomedical Engineering Letters, 2014 - Springer
Microelectrode array (MEA) technology is a widely used platform for the study of in vitro
neural networks as it can either record or stimulate neurons by accessing multiple sites of …

Parameters for burst detection

DJ Bakkum, M Radivojevic, U Frey, F Franke… - Frontiers in …, 2014 - frontiersin.org
Bursts of action potentials within neurons and throughout networks are believed to serve
roles in how neurons handle and store information, both in vivo and in vitro. Accurate …

Recording large extracellular spikes in microchannels along many axonal sites from individual neurons

MK Lewandowska, DJ Bakkum, SB Rompani… - PloS one, 2015 - journals.plos.org
The numerous connections between neuronal cell bodies, made by their dendrites and
axons, are vital for information processing in the brain. While dendrites and synapses have …

Large‐Area Field Potential Imaging Having Single Neuron Resolution Using 236 880 Electrodes CMOS‐MEA Technology

I Suzuki, N Matsuda, X Han, S Noji… - Advanced …, 2023 - Wiley Online Library
The electrophysiological technology having a high spatiotemporal resolution at the single‐
cell level and noninvasive measurements of large areas provide insights on underlying …

Transcranial low-intensity ultrasound stimulation for treating central nervous system disorders: A promising therapeutic application

YY Hu, G Yang, XS Liang, XS Ding, DE Xu, Z Li… - Frontiers in …, 2023 - frontiersin.org
Transcranial ultrasound stimulation is a neurostimulation technique that has gradually
attracted the attention of researchers, especially as a potential therapy for neurological …