Dyslipidemia in muscular dystrophy: A systematic review and meta-analysis
Z Sun, X Wang, Z White, C Dormuth… - Journal of …, 2023 - content.iospress.com
Background: Muscular dystrophies (MDs) are characterized by chronic muscle wasting but
also poorly understood metabolic co-morbidities. We have recently shown that Duchenne …
also poorly understood metabolic co-morbidities. We have recently shown that Duchenne …
[HTML][HTML] Skeletal muscle disorders as risk factors for type 2 diabetes.
The incidence and prevalence of muscular disorders and of type 2 diabetes (T2D) is
increasing and both represent highly significant healthcare problems, both economically …
increasing and both represent highly significant healthcare problems, both economically …
[HTML][HTML] Hic1 identifies a specialized mesenchymal progenitor population in the embryonic limb responsible for bone superstructure formation
M Arostegui, RW Scott, TM Underhill - Cell Reports, 2023 - cell.com
The musculoskeletal system relies on the integration of multiple components with diverse
physical properties, such as striated muscle, tendon, and bone, that enable locomotion and …
physical properties, such as striated muscle, tendon, and bone, that enable locomotion and …
Influenza A virus infection activates STAT3 to enhance SREBP2 expression, cholesterol biosynthesis, and virus replication
J Zhang, Y Wu, Y Wang, P Liu, K Liu, J Sun, P Zhang… - Iscience, 2024 - cell.com
Cellular cholesterol plays an important role in influenza A virus (IAV) endocytosis and
replication. However, how IAV infection regulates cholesterol biosynthesis remains poorly …
replication. However, how IAV infection regulates cholesterol biosynthesis remains poorly …
Comparative lipidomic and metabolomic profiling of mdx and severe mdx-apolipoprotein e-null mice
Despite its notoriously mild phenotype, the dystrophin-deficient mdx mouse is the most
common model of Duchenne muscular dystrophy (DMD). By mimicking a human DMD …
common model of Duchenne muscular dystrophy (DMD). By mimicking a human DMD …
Apolipoprotein E knockout, but not cholesteryl ester transfer protein (CETP)-associated high-density lipoprotein cholesterol (HDL-C) lowering, exacerbates muscle …
Z Sun, Z White, M Theret, P Bernatchez - Lipids in Health and Disease, 2024 - Springer
Background Dysferlin-deficient limb-girdle muscular dystrophy type 2B (Dysf) mice are
notorious for their mild phenotype. Raising plasma total cholesterol (CHOL) via …
notorious for their mild phenotype. Raising plasma total cholesterol (CHOL) via …
Humanization of the mdx Mouse Phenotype for Duchenne Muscular Dystrophy Modeling: A Metabolic Perspective
G Donen, N Milad, P Bernatchez - Journal of Neuromuscular …, 2023 - content.iospress.com
Duchenne muscular dystrophy (DMD) is a severe form of muscular dystrophy (MD) that is
characterized by early muscle wasting and lethal cardiorespiratory failure. While the mdx …
characterized by early muscle wasting and lethal cardiorespiratory failure. While the mdx …
Effects of HMGCR deficiency on skeletal muscle development
M Gunasekaran, HR Littel, NM Wells, J Turner… - bioRxiv, 2024 - biorxiv.org
Pathogenic variants in HMGCR were recently linked to a limb-girdle muscular dystrophy
(LGMD) phenotype. The protein product HMG CoA reductase (HMGCR) catalyzes a key …
(LGMD) phenotype. The protein product HMG CoA reductase (HMGCR) catalyzes a key …
Effects of HMG CoA reductase (HMGCR) deficiency on skeletal muscle development
M Gunasekaran, HR Littel, NM Wells, J Turner… - The FEBS … - Wiley Online Library
Pathogenic variants in HMGCR were recently linked to a limb‐girdle muscular dystrophy
(LGMD) phenotype. The protein product HMG CoA reductase (HMGCR) catalyzes a key …
(LGMD) phenotype. The protein product HMG CoA reductase (HMGCR) catalyzes a key …
Psoas major muscle mass and upper limb muscle strength are the main factors influencing the rate of HDL-cholesterol within the target in T2DM patients
S Guo, Z Han, W Cheng, Z Zhang, J Liu, Y Wang… - 2023 - researchsquare.com
Background Achieving lipid control standards is one of the most important measures to slow
down the development of diabetic complications. Clinically, effective drugs have been …
down the development of diabetic complications. Clinically, effective drugs have been …