[HTML][HTML] Dynamics in Cre-loxP site-specific recombination
MP Foster, MJ Benedek, TD Billings… - Current opinion in …, 2024 - Elsevier
Cre recombinase is a phage-derived enzyme that has found utility for precise manipulation
of DNA sequences. Cre recognizes and recombines pairs of loxP sequences characterized …
of DNA sequences. Cre recognizes and recombines pairs of loxP sequences characterized …
[HTML][HTML] Conformational dynamics promotes disordered regions from function-dispensable to essential in evolved site-specific DNA recombinases
C Guillén-Pingarrón, PM Guillem-Gloria, A Soni… - Computational and …, 2022 - Elsevier
Protein intrinsically disordered regions (IDRs) play pivotal roles in molecular recognition and
regulatory processes through structural disorder-to-order transitions. To understand and …
regulatory processes through structural disorder-to-order transitions. To understand and …
Kinetic properties of optogenetic DNA editing by LiCre-loxP
A Dufour, H Duplus-Bottin, T Boukeke-Lesplulier… - bioRxiv, 2024 - biorxiv.org
Previously, we developed an optogenetic tool made of a single chimeric protein called LiCre
that enables the edition of specific changes in the genome of live cells with blue light via …
that enables the edition of specific changes in the genome of live cells with blue light via …
DNA microcircles-The promising tool for in vivo studies of the behavior of non-canonical DNA
AA Vetcher, YM Stanishevskiy - Progress in Biophysics and Molecular …, 2022 - Elsevier
The paper discusses the reasons for the resurrection of the term DNA microcircles through
the change of its definition to “topologically closed DNA circles with the length less than 1 …
the change of its definition to “topologically closed DNA circles with the length less than 1 …
[PDF][PDF] Imperfection as the foundation of life, imprinting of DNA sequence on water.
IV Savelev, MM Rempel, OO Polesskaya, RA Miller… - researchgate.net
A novel model is presented of DNA-water interactions within the cell nucleus, proposing a
mechanism for continuous self-reorganization of water structures around DNA. The model …
mechanism for continuous self-reorganization of water structures around DNA. The model …
[PDF][PDF] A model and genomic evidence of imprinting DNA sequence on water structure
IV Savelev, MM Rempel, AV Vikhorev, OO Polesskaya… - researchgate.net
A novel model is presented of DNA-water interactions within the cell nucleus, proposing a
mechanism for continuous self-reorganization of water structures around DNA. The model …
mechanism for continuous self-reorganization of water structures around DNA. The model …
Structure and dynamics in site-specific recombination
N Wagner - 2022 - rave.ohiolink.edu
The field of gene editing, which offers opportunities to treat genetic mutations and diseases
at the level of the gene itself, has garnered a great deal of interest in recent years, especially …
at the level of the gene itself, has garnered a great deal of interest in recent years, especially …