Iron is the most abundant transition metal in the human body and its bioavailability is
stringently controlled. In particular, iron is tightly bound to host proteins such as transferrin to …

Chronic obstructive pulmonary disease (COPD) is the fourth leading cause of death in the
United States. The precise role of bacterial infection in the course and pathogenesis of …

Short-sequence DNA repeat (SSR) loci can be identified in all eukaryotic and many
prokaryotic genomes. These loci harbor short or long stretches of repeated nucleotide …

A new group of potent antibacterial compounds, non‐iron metalloporphyrins (MPs), is
described. MPs possess a strong antibacterial activity against Gram‐positive bacteria, Gram …

Corynebacterium diphtheriae was examined for the ability to utilize various host compounds
as iron sources. C. diphtheriae C7 (-) acquired iron from heme, hemoglobin, and transferrin …

Efficient iron acquisition is critical for an invading microbe's survival and virulence. Most of
the iron in mammals is incorporated into heme, which can be plundered by certain bacterial …

Staphylococcus aureus is an extremely adaptable pathogen causing a wide variety of
infections. Staphylococcal surface proteins that directly interact with host extracellular …

An extensive amount of new knowledge on bacterial systems involved in heme processing
has been accumulated in the last 10 years. We discuss common themes in heme transport …

Non-typable Haemophilus influenzae is a common commensal organism in the human
upper respiratory tract and an important cause of localized respiratory tract disease. The …

The abilities of two bacterial active heme transporters, HmbR of Neisseria meningitidis and
HemR of Yersinia enterocolitica, to use different heme sources were compared. While …