New insights into glial scar formation after spinal cord injury

AP Tran, PM Warren, J Silver - Cell and tissue research, 2022 - Springer
Severe spinal cord injury causes permanent loss of function and sensation throughout the
body. The trauma causes a multifaceted torrent of pathophysiological processes which …

Integrative biology of injury in animals

CW Rennolds, AE Bely - Biological Reviews, 2023 - Wiley Online Library
Mechanical injury is a prevalent challenge in the lives of animals with myriad potential
consequences for organisms, including reduced fitness and death. Research on animal …

Identification of rare, transient post-mitotic cell states that are induced by injury and required for whole-body regeneration in Schmidtea mediterranea

BW Benham-Pyle, CE Brewster, AM Kent… - Nature cell …, 2021 - nature.com
Regeneration requires the coordination of stem cells, their progeny and distant differentiated
tissues. Here, we present a comprehensive atlas of whole-body regeneration in Schmidtea …

Evolution of regeneration in animals: A tangled story

A Elchaninov, G Sukhikh, T Fatkhudinov - Frontiers in Ecology and …, 2021 - frontiersin.org
The evolution of regenerative capacity in multicellular animals represents one of the most
complex and intriguing problems in biology. How could such a seemingly advantageous trait …

Animal regeneration in the era of transcriptomics

L Bideau, P Kerner, J Hui, M Vervoort… - Cellular and Molecular …, 2021 - Springer
Animal regeneration, the ability to restore a lost body part, is a process that has fascinated
scientists for centuries. In this review, we first present what regeneration is and how it relates …

Recent progress in reconstructing lophotrochozoan (spiralian) phylogeny

C Bleidorn - Organisms Diversity & Evolution, 2019 - Springer
Lophotrochozoa (also called Spiralia), the sister taxon of Ecdysozoa, includes animal taxa
with disparate body plans such as the segmented annelids, the shell bearing molluscs and …

Comparative study in zebrafish and medaka unravels the mechanisms of tissue regeneration

K Chowdhury, S Lin, SL Lai - Frontiers in Ecology and Evolution, 2022 - frontiersin.org
Tissue regeneration has been in the spotlight of research for its fascinating nature and
potential applications in human diseases. The trait of regenerative capacity occurs diversely …

A pan‐metazoan concept for adult stem cells: the wobbling Penrose landscape

B Rinkevich, L Ballarin, P Martinez… - Biological …, 2022 - Wiley Online Library
Adult stem cells (ASCs) in vertebrates and model invertebrates (eg Drosophila
melanogaster) are typically long‐lived, lineage‐restricted, clonogenic and quiescent cells …

A novel approach to comparative RNA-seq does not support a conserved set of orthologs underlying animal regeneration

NC Sierra, N Olsman, L Yi, L Pachter… - Genome Biology and …, 2024 - academic.oup.com
Molecular studies of animal regeneration typically focus on conserved genes and signaling
pathways that underlie morphogenesis. To date, a holistic analysis of gene expression …

Morphallaxis versus epimorphosis? Cellular and molecular aspects of regeneration and asexual reproduction in annelids

RP Kostyuchenko, VV Kozin - Biology Bulletin, 2020 - Springer
This article addresses the question of the role of morphallactic and epimorphic events in
regeneration and asexual reproduction in annelids. It was shown that tissue reorganization …