The neuropsychiatry of Parkinson's disease: advances and challenges

D Weintraub, D Aarsland, KR Chaudhuri… - The Lancet …, 2022 - thelancet.com
In people with Parkinson's disease, neuropsychiatric signs and symptoms are common
throughout the disease course. These symptoms can be disabling and as clinically relevant …

Depression in patients with Parkinson's disease: current understanding of its neurobiology and implications for treatment

S Prange, H Klinger, C Laurencin, T Danaila… - Drugs & Aging, 2022 - Springer
Depression is one of the most frequent and burdensome non-motor symptoms in
Parkinson's disease (PD), across all stages. Even when its severity is mild, PD depression …

Neuroimaging of anxiety in Parkinson's disease: a systematic review

G Carey, M Görmezoğlu, JJA de Jong… - Movement …, 2021 - Wiley Online Library
Background The aim of this systematic review was (1) to identify the brain regions involved
in anxiety in Parkinson's disease (PD) based on neuroimaging studies and (2) to interpret …

Network imaging biomarkers: insights and clinical applications in Parkinson's disease

KA Schindlbeck, D Eidelberg - The Lancet Neurology, 2018 - thelancet.com
Parkinson's disease presents several practical challenges: it can be difficult to distinguish
from atypical parkinsonian syndromes, clinical ratings can be insensitive as markers of …

[HTML][HTML] Lipopolysaccharide animal models of Parkinson's disease: Recent progress and relevance to clinical disease

I Deng, F Corrigan, G Zhai, XF Zhou… - Brain, behavior, & …, 2020 - Elsevier
Parkinson's disease (PD) is one of the most common neurodegenerative movement
disorders which is characterised neuropathologically by progressive loss of dopaminergic …

Serotonergic and dopaminergic lesions underlying parkinsonian neuropsychiatric signs

A Maillet, E Météreau, L Tremblay, E Favre… - Movement …, 2021 - Wiley Online Library
Background Parkinson's disease (PD) is characterized by heterogeneous motor and
nonmotor manifestations related to alterations in monoaminergic neurotransmission …

Dysfunctional limbic circuitry underlying freezing of gait in Parkinson's disease

M Gilat, KAE Martens, O Miranda-Domínguez, I Arpan… - Neuroscience, 2018 - Elsevier
Freezing of gait (FOG) is a poorly understood symptom affecting many patients with
Parkinson's disease (PD). Despite growing evidence of a behavioral link between anxiety …

A novel CERNNE approach for predicting Parkinson's Disease-associated genes and brain regions based on multimodal imaging genetics data

X Bi, X Hu, Y Xie, H Wu - Medical Image Analysis, 2021 - Elsevier
The detection and pathogenic factors analysis of Parkinson's disease (PD) has a practical
significance for its diagnosis and treatment. However, the traditional research paradigms are …

Early limbic microstructural alterations in apathy and depression in de novo Parkinson's disease

S Prange, E Metereau, A Maillet… - Movement …, 2019 - Wiley Online Library
Background Whether structural alterations underpin apathy and depression in de novo
parkinsonian patients is unknown. The objectives of this study were to investigate whether …

Investigation on sleep and mental health of patients with Parkinson's disease during the Coronavirus disease 2019 pandemic

Y Xia, L Kou, G Zhang, C Han, J Hu, F Wan, S Yin… - Sleep medicine, 2020 - Elsevier
Background The coronavirus disease 2019 (COVID-19) pandemic is adversely affecting
sleep quality and mental health, especially in individuals with chronic disease such as …