Inflammation is associated with the development and malignant progression of most
cancers. As most of the cell types involved in cancer-associated inflammation are genetically …

Epigenetic mechanisms comprising DNA methylation, histone modifications, and noncoding
RNAs affect chromatin structure and regulate gene expression. These mechanisms control …

Aspirin as a possible treatment of cancer has been of increasing interest for over 50 years,
but the balance of the risks and benefits remains a point of contention. We summarise the …

Inflammation is highly associated with colon carcinogenesis. Epigenetic mechanisms could
play an important role in the initiation and progression of colon cancer. Curcumin, a dietary …

Chronic inflammation and oxidative stress are common and co-substantial pathological
processes accompanying and contributing to cancers. Numerous epidemiological studies …

Molecular mechanisms associated with inflammation-promoted tumorigenesis have become
an important topic in cancer research. Various abnormal epigenetic changes, including DNA …

Simple Summary Epigenetics encompasses all the modifications that occur within cells that
are independent of gene mutations. The environment is the main influencer of these …

Epigenetics comprise a diverse array of reversible and dynamic modifications to the cell's
genome without implicating any DNA sequence alterations. Both the external environment …

Background and Purpose Colorectal cancer is the third most common cancer worldwide.
HER2 and HER3 are two members of human epidermal receptor family of tyrosine kinase …

Colorectal cancer is one of the most common gastrointestinal malignancies in humans,
affecting approximately 1.8 million people worldwide. This disease has a major social …