Optical coherence tomography for three-dimensional imaging in the biomedical field: a review

S Zheng, Y Bai, Z Xu, P Liu, G Ni - Frontiers in Physics, 2021 - frontiersin.org
Optical coherence tomography (OCT) has become a novel approach to noninvasive imaging
in the past three decades, bringing a significant potential to biological research and medical …

Nano-optic endoscope for high-resolution optical coherence tomography in vivo

H Pahlevaninezhad, M Khorasaninejad, YW Huang… - Nature …, 2018 - nature.com
Acquisition of high-resolution images from within internal organs using endoscopic optical
imaging has numerous clinical applications. However, difficulties associated with optical …

Histological validation of in vivo assessment of cancer tissue inhomogeneity and automated morphological segmentation enabled by Optical Coherence Elastography

AA Plekhanov, MA Sirotkina, AA Sovetsky… - Scientific reports, 2020 - nature.com
We present a non-invasive (albeit contact) method based on Optical Coherence
Elastography (OCE) enabling the in vivo segmentation of morphological tissue constituents …

Recent advances in optical elastography and emerging opportunities in the basic sciences and translational medicine

N Leartprapun, SG Adie - Biomedical Optics Express, 2023 - opg.optica.org
Optical elastography offers a rich body of imaging capabilities that can serve as a bridge
between organ-level medical elastography and single-molecule biophysics. We review the …

Analysis of spatial resolution in phase-sensitive compression optical coherence elastography

MS Hepburn, P Wijesinghe, L Chin… - Biomedical optics …, 2019 - opg.optica.org
Optical coherence elastography (OCE) is emerging as a method to image the mechanical
properties of tissue on the microscale. However, the spatial resolution, a main advantage of …

Analysis of strain estimation methods in phase-sensitive compression optical coherence elastography

J Li, E Pijewska, Q Fang, M Szkulmowski… - Biomedical Optics …, 2022 - opg.optica.org
In compression optical coherence elastography (OCE), deformation is quantified as the local
strain at each pixel in the OCT field-of-view. A range of strain estimation methods have been …

Three-dimensional imaging of cell and extracellular matrix elasticity using quantitative micro-elastography

MS Hepburn, P Wijesinghe, LG Major, J Li… - Biomedical Optics …, 2020 - opg.optica.org
Recent studies in mechanobiology have revealed the importance of cellular and
extracellular mechanical properties in regulating cellular function in normal and disease …

Analysis of sensitivity in quantitative micro-elastography

J Li, MS Hepburn, L Chin, A Mowla… - Biomedical Optics …, 2021 - opg.optica.org
Quantitative micro-elastography (QME), a variant of compression optical coherence
elastography (OCE), is a technique to image tissue elasticity on the microscale. QME has …

Novel endoscope with increased depth of field for imaging human nasal tissue by microscopic optical coherence tomography

H Schulz-Hildebrandt, M Pieper, C Stehmar… - Biomedical optics …, 2018 - opg.optica.org
Intravital microscopy (IVM) offers the opportunity to visualize static and dynamic changes of
tissue on a cellular level. It is a valuable tool in research and may considerably improve …

Biomechanical assessment of chronic liver injury using quantitative micro-elastography

A Mowla, R Belford, J Köhn-Gaone, N Main… - Biomedical Optics …, 2022 - opg.optica.org
Hepatocellular carcinoma is one of the most lethal cancers worldwide, causing almost
700,000 deaths annually. It mainly arises from cirrhosis, which, in turn, results from chronic …