Polymyxins are important lipopeptide antibiotics that serve as the last-line defense against
multidrug-resistant (MDR) Gram-negative bacterial infections. Worryingly, the clinical utility …

Antibiotic resistance is a great concern, which leads to global public health risks and
ecological and environmental risks. The presence of antibiotic-resistant genes and antibiotic …

Objectives To investigate the occurrence of antibiotic residues in different types of
environmental samples including water samples in rural Shandong province, China. Further …

The emergence and spread of mobile colistin (COL) resistance (mcr) genes jeopardize the
efficacy of COL, a last resort antibiotic for treating deadly infections. COL has been used in …

MCR-1 is a lipid A modifying enzyme that confers resistance to the antibiotic colistin. Here,
we analyse the impact of MCR-1 expression on E. coli morphology, fitness, competitiveness …

Background: The rapidly increasing dissemination of carbapenem-resistant
Enterobacteriaceae (CRE) in both humans and animals poses a global threat to public …

The detection and rapid spread of colistin-resistant Enterobacteriaceae carrying the mcr-1
gene has created an urgent need to strengthen surveillance. In this study, eight clonally …

Raoultella ornithinolytica is an encapsulated Gram-negative, oxidase-negative, catalase-
positive, aerobic, non-motile rod that belongs to the Enterobacteriaceae family. This …

Antibiotic resistance is one of the greatest public-health challenges worldwide, especially
with regard to Gram-negative bacteria (GNB). Carbapenems are the β-lactam antibiotics of …

Abstract Lake Tai is China's third largest freshwater lake and an important water resource for
agriculture, industrial sectors, and as drinking water for several large cities. In this study, the …