Obesity and type 2 diabetes: two diseases with a need for combined treatment strategies-EASO can lead the way

DR Leitner, G Frühbeck, V Yumuk, K Schindler, D Micic… - Obesity facts, 2017 - karger.com
Obesity is a chronic metabolic disease affecting adults and children worldwide. It has
become one of the leading causes of death, as obesity is known to be the main risk factor for …

Increased mortality in schizophrenia due to cardiovascular disease–a non-systematic review of epidemiology, possible causes, and interventions

PA Ringen, JA Engh, AB Birkenaes, I Dieset… - Frontiers in …, 2014 - frontiersin.org
Background: Schizophrenia is among the major causes of disability worldwide and the
mortality from cardiovascular disease (CVD) is significantly elevated. There is a growing …

Antipsychotics, metabolic adverse effects, and cognitive function in schizophrenia

NE MacKenzie, C Kowalchuk, SM Agarwal… - Frontiers in …, 2018 - frontiersin.org
Cognitive impairment is a core symptom domain of schizophrenia. The effect of
antipsychotics, the cornerstone of treatment in schizophrenia, on this domain is not fully …

[HTML][HTML] Metabolic syndrome in people with schizophrenia: a review

M De Hert, V Schreurs, D Vancampfort… - World …, 2009 - ncbi.nlm.nih.gov
Metabolic syndrome and other cardiovascular risk factors are highly prevalent in people with
schizophrenia. Patients are at risk for premature mortality and overall have limited access to …

[HTML][HTML] Early intervention in psychosis: concepts, evidence and future directions

PD McGorry, E Killackey, A Yung - World psychiatry, 2008 - ncbi.nlm.nih.gov
The rise of the early intervention paradigm in psychotic disorders represents a maturing of
the therapeutic approach in psychiatry, as it embraces practical preventive strategies which …

Antipsychotic-induced weight gain in first-episode psychosis patients: a meta-analysis of differential effects of antipsychotic medications

C Tek, S Kucukgoncu, S Guloksuz, SW Woods… - Focus, 2016 - Am Psychiatric Assoc
Aim: The first-episode psychosis (FEP) represents a critical period to prevent cardiovascular
and metabolic morbidity decades later. Antipsychotic (AP)-induced weight gain is one …

Systematic review of early cardiometabolic outcomes of the first treated episode of psychosis

DL Foley, KI Morley - Archives of general psychiatry, 2011 - jamanetwork.com
Objectives: To assess the methods and reporting of cardiometabolic outcome studies of the
first treated episode of psychosis, review key findings, and suggest directions for future …

Past and present progress in the pharmacologic treatment of schizophrenia

JM Kane, CU Correll - The Journal of clinical psychiatry, 2010 - psychiatrist.com
Despite treatment advances over the past decades, schizophrenia remains one of the most
severe psychiatric disorders that is associated with a chronic relapsing course and marked …

Antipsychotic-induced weight gain in chronic and first-episode psychotic disorders: a systematic critical reappraisal

M Alvarez-Jimenez, C Gonzalez-Blanch… - CNS drugs, 2008 - Springer
Antipsychotic-induced weight gain is an important issue in the treatment of psychotic
illnesses, and affects 80% of individuals being treated with antipsychotic drugs. However …

Which comes first: atypical antipsychotic treatment or cardiometabolic risk?

SM Stahl, L Mignon, JM Meyer - Acta Psychiatrica Scandinavica, 2009 - Wiley Online Library
Objective: To provide an overview for practicing clinicians on the pharmacological basis of
cardiometabolic risk induced by antipsychotic drugs in patients with serious mental illness …