Methylation-related genes involved in renal carcinoma progression

JM Zamora-Fuentes, E Hernández-Lemus… - Frontiers in …, 2023 - frontiersin.org
Renal carcinomas are a group of malignant tumors often originating in the cells lining the
small tubes in the kidney responsible for filtering waste from the blood and urine production …

Loss of long distance co-expression in lung cancer

SD Andonegui-Elguera, JM Zamora-Fuentes… - Frontiers in …, 2021 - frontiersin.org
Lung cancer is one of the deadliest, most aggressive cancers. Abrupt changes in gene
expression represent an important challenge to understand and fight the disease. Gene co …

k-core genes underpin structural features of breast cancer

R Dorantes-Gilardi, D García-Cortés… - Scientific Reports, 2021 - nature.com
Gene co-expression networks (GCNs) have been developed as relevant analytical tools for
the study of the gene expression patterns behind complex phenotypes. Determining the …

Gene expression and co-expression networks are strongly altered through stages in clear cell renal carcinoma

JM Zamora-Fuentes, E Hernández-Lemus… - Frontiers in …, 2020 - frontiersin.org
Clear cell renal carcinoma (ccRC) is a highly heterogeneous and progressively malignant
disease. Analyzing ccRC progression in terms of modifications at the molecular and genetic …

Luminal a breast cancer co-expression network: Structural and functional alterations

D García-Cortés, E Hernández-Lemus… - Frontiers in …, 2021 - frontiersin.org
Luminal A is the most common breast cancer molecular subtype in women worldwide.
These tumors have characteristic yet heterogeneous alterations at the genomic and …

Multilayer approach reveals organizational principles disrupted in breast cancer co-expression networks

R Dorantes-Gilardi, D García-Cortés… - Applied Network …, 2020 - Springer
The study of co-expression programs in the context of cancer can help to elucidate the
genetic mechanisms that are altered and lead to the disease. The identification of gene co …

Gene co-expression is distance-dependent in breast cancer

D García-Cortés, G de Anda-Jáuregui, C Fresno… - Frontiers in …, 2020 - frontiersin.org
Breast carcinomas are characterized by anomalous gene regulatory programs. As is well-
known, gene expression programs are able to shape phenotypes. Hence, the understanding …

Chemopreventive effect of pomegranate and cocoa extracts on ultraviolet radiation-induced photocarcinogenesis in SKH-1 mice

FJ Gómez-García, A López López… - PLoS …, 2020 - journals.plos.org
Non-melanoma skin cancer (NMSC) has a high and increasing incidence all over the world.
Solar radiation is the main aetiology for humans. Although most research into …

Loss of long-range co-expression is a common trait in cancer

D Garcia-Cortes, E Hernandez-Lemus… - bioRxiv, 2022 - biorxiv.org
Cancer cells display common traits and enabling-characteristics previously described as the
Hallmarks of Cancer. These occur alongside alterations in the regulatory mechanisms …

Spatial organization of the gene regulatory program: an information theoretical approach to breast cancer transcriptomics

G de Anda-Jáuregui, J Espinal-Enriquez… - Entropy, 2019 - mdpi.com
Gene regulation may be studied from an information-theoretic perspective. Gene regulatory
programs are representations of the complete regulatory phenomenon associated to each …