During the COVID-19 pandemic in a modern era, there is a global consensus on the need
for the rapid development of a vaccine against SARS-CoV-2 for effective and sustainable …

Despite the availability of a safe and effective vaccine, in 2018, around 350,000 measles
cases were reported worldwide, which resulted in an estimate of 142,300 deaths from …

Motivation: The human leukocyte antigen (HLA) gene cluster plays a crucial role in adaptive
immunity and is thus relevant in many biomedical applications. While next-generation …

Background. Defining the parameters that modulate vaccine responses in African
populations will be imperative to design effective vaccines for protection against HIV …

A measles outbreak occurred in New York City. All cases had prior evidence of measles
immunity. Symptoms were consistent with measles. Laboratory results indicated secondary …

Background. The relevance of antibodies (Abs) in the defense against Mycobacterium
tuberculosis infection remains uncertain. We investigated the role of Abs to the …

The outcome of Mycobacterium tuberculosis infection and the immunological response to
the bacillus Calmette-Guerin (BCG) vaccine are highly variable in humans. Deciphering the …

The conceptualisation of autistic spectrum disorder and Alzheimer's disease has undergone
something of a paradigm shift in recent years and rather than being viewed as single …

Chagas disease is a neglected disease caused by Trypanosoma cruzi parasites. Most
diagnosis is based on serological tests, but the lack of a gold standard test complicates the …

In a blinded randomized trial, preoperative receipt of the Merck V710 Staphylococcus
aureus vaccine was associated with a higher mortality rate than placebo in patients who …