Estrogens have historically been associated with female reproduction, but work over the last
two decades established that estrogens and their main nuclear receptors (ESR1 and ESR2) …

Puberty is characterized by major changes in the anatomy and function of reproductive
organs. Androgen activity is low before puberty, but during pubertal development, the testes …

Estrogen has always been considered the female hormone and testosterone the male
hormone. However, estrogen's presence in the testis and deleterious effects of estrogen …

As there is limited literature on paratesticular tumors of müllerian and mesothelial origin, we
reviewed archived cases of serous borderline tumors (n= 15), low-grade serous carcinoma …

Abstract Paired Box 8 (PAX8) is a lineage-specific transcription factor that has essential
roles during embryogenesis and tumorigenesis. The importance of PAX8 in the …

A comprehensive immunohistochemical ontogeny of the developing human fetal testis has
remained incomplete in the literature to date. We collected human fetal testes from 8 to 21 …

Adenocarcinoma of the rete testis is rare and its etiological and pathologic characteristics
are not well studied. We therefore investigated the clinical, morphologic, and …

The nested variant of urothelial carcinoma, a frequent mimic of benign lesions on limited
specimens, has been associated with high-stage disease including metastases at …

Endolymphatic sac tumors (ELSTs) are rare, slowly growing temporal bone neoplasms
which show a high association with von Hippel-Lindau (VHL) syndrome. The …

Mesonephric lesions in the female genital tract are uncommon, with those arising from the
upper tract being much less frequent than those developing in the lower tract (mesonephric …