Smoking is a major risk factor for a variety of diseases, including cancer and immune-
mediated inflammatory diseases. Tobacco smoke contains a mixture of chemicals, including …

Traditional biochemical methods for enzyme detection are mainly based on antibody-based
immunoassays, which lack the ability to monitor the spatiotemporal distribution and, in …

Non-alcoholic fatty liver disease (NAFLD) is a term that covers a range of hepatic disorders
involving fat deposits in the liver. NAFLD begins with simple steatosis and progresses into …

To maintain the stability and integrity of cellular genomic DNA, DNA repair enzymes catalyze
the repair of DNA damage caused by exogenous and endogenous factors through various …

DNA-modifying enzymes participate in various genetic functions (eg, DNA replication,
repairing, and recombination) through alternating certain DNA sequence, and the …

Oxidatively induced DNA damage is caused in living organisms by endogenous and
exogenous reactive species. DNA lesions resulting from this type of damage are mutagenic …

Endogenous and exogenous sources cause oxidatively induced DNA damage in living
organisms by a variety of mechanisms. The resulting DNA lesions are mutagenic and …

Genome stability is essential for maintaining cellular and organismal homeostasis, but it is
subject to many threats. One ubiquitous threat is from a class of compounds known as …

Oxidative damage produced by reactive oxygen species (ROS) has been implicated in the
etiology and pathology of many health conditions, including a large number of chronic …

Oxidative DNA damage is considered to play an important role in pathophysiological
processes, ageing and cancer. So far major interest has been on measuring 8-hydroxy-2 …