Developing neurons connect in specific and stereotyped ways to form the complex circuits
that underlie brain function. By comparison to earlier steps in neural development, progress …

Protocadherins (Pcdhs) are cell adhesion molecules that belong to the cadherin
superfamily, and are subdivided into clustered (cPcdhs) and non-clustered Pcdhs (ncPcdhs) …

Stochastic activation of clustered Protocadherin (Pcdh) α, β, and γ genes generates a cell-
surface identity code in individual neurons that functions in neural circuit assembly. Here, we …

Olfactory sensory neurons (OSNs) convert the stochastic choice of one of> 1,000 olfactory
receptor (OR) genes into precise and stereotyped axon targeting of OR-specific glomeruli in …

Serotonergic neurons project their axons pervasively throughout the brain and innervate
various target fields in a space-filling manner, leading to tiled arrangements of their axon …

The neocortex consists of a vast number of diverse neurons that form distinct layers and
intricate circuits at the single-cell resolution to support complex brain functions. Diverse cell …

Sensory neurons in the mouse eye and nose have unusual chromatin organization. Here we
report their three-dimensional (3D) genome structure at 20-kilobase (kb) resolution …

Abstracts Early B cell lymphopoiesis depends on E2A, Ebf1, Pax5 and Ikaros family
members. In the present study, we used acute protein degradation in mice to identify direct …

Advances in genomics are opening new windows into the biology of schizophrenia. Though
common variants individually have small effects on disease risk, GWAS provide a powerful …

Disruption of cell division cycle associated 7 (CDCA7) has been linked to aberrant DNA
hypomethylation, but the impact of DNA methylation loss on transcription has not been …