Alzheimer disease (AD) is the most common contributor to dementia in the world, but
strategies that slow or prevent its clinical progression have largely remained elusive, until …

Tauopathies are a heterogeneous group of neurodegenerative disorders that are
characterised by the aggregation of the microtubule-associated protein tau into filamentous …

Objective To assess the presence of brain and systemic inflammation in subjects newly
diagnosed with Parkinson's disease (PD). Background Evidence for a pathophysiologic role …

Abstract Background Coronavirus disease 2019 (COVID-19) patients initially develop
respiratory symptoms, but they may also suffer from neurological symptoms. People with …

Introduction The 18-kDa translocator protein (TSPO) is increasingly recognized as a
molecular target for PET imaging of inflammatory responses in various central nervous …

The COVID-19 pandemic caused by SARS-CoV-2 has triggered a consequential public
health crisis of post-acute sequelae of COVID-19 (PASC), sometimes referred to as long …

Metabolic risk factors are associated with peripheral low-grade inflammation and an
increased risk for dementia. We evaluated if metabolic risk factors ie insulin resistance, body …

Reactive astrogliosis accompanies the two neuropathological hallmarks of Alzheimer's
disease (AD)—Aβ plaques and neurofibrillary tangles—and parallels neurodegeneration in …

Alzheimer's disease (AD) is a brain network disorder where pathological proteins
accumulate through networks and drive cognitive decline. Yet, the role of network …

It is becoming increasingly apparent that neuroinflammation plays a critical role in an array
of neurological and psychiatric disorders. Recent studies have demonstrated the potential of …