Associations of depression and anxiety symptoms in childhood and adolescence with epigenetic aging
Background Childhood anxiety and depression symptoms are potential risk factors for
accelerated biological aging. In child and adolescent twins, we tested whether these …
accelerated biological aging. In child and adolescent twins, we tested whether these …
Epigenome-wide analysis identifies methylome profiles linked to obsessive-compulsive disorder, disease severity, and treatment response
Obsessive-compulsive disorder (OCD) is a prevalent mental disorder affecting~ 2–3% of the
population. This disorder involves genetic and, possibly, epigenetic risk factors. The …
population. This disorder involves genetic and, possibly, epigenetic risk factors. The …
Bioinformatics gene analysis for potential biomarkers and therapeutic targets of Parkinson's disease based on neutrophil extracellular traps
Q Wang, Y Gu, J Chen, X Liu, C Xie… - Frontiers in Aging …, 2024 - frontiersin.org
Introduction Neutrophil extracellular traps (NETs) provide key innate immune mechanisms,
and studies have shown innate immunity and adaptive immunity are directly linked to …
and studies have shown innate immunity and adaptive immunity are directly linked to …
Methylation status of LDLR, PCSK9 and LDLRAP1 is associated with cardiovascular events in familial hypercholesterolemia
E Silva Rodrigues Marçal, JB Borges, GM Bastos… - …, 2024 - Taylor & Francis
Aim: Methylation of LDLR, PCSK9 and LDLRAP1 CpG sites was assessed in patients with
familial hypercholesterolemia (FH). Methods: DNA methylation of was analyzed by …
familial hypercholesterolemia (FH). Methods: DNA methylation of was analyzed by …
Identifying Novel Proteins for Chronic Pain: Integration of Human Brain Proteomes and Genome-wide Association Data
H Huang, F Ji, C Hu, J Huang, F Liu, Z Han, L Liu… - The Journal of …, 2024 - Elsevier
Numerous genome-wide association studies have identified risk genes for chronic pain, yet
the mechanisms by which genetic variants modify susceptibility have remained elusive. We …
the mechanisms by which genetic variants modify susceptibility have remained elusive. We …
Clinical description and epigenetic profiling of a new Danish OCD case-control cohort
NH Staunstrup, A Starnawska, J Bybjerg-Grauholm… - 2023 - researchsquare.com
Background Obsessive compulsive disorder (OCD) is a frequent and severe
neuropsychiatric disorder, with cardinal features being obsessions and compulsions. The …
neuropsychiatric disorder, with cardinal features being obsessions and compulsions. The …