Cancer is a complex disease resulting from the genetic and epigenetic disruption of normal
cells. The mechanistic understanding of the pathways involved in tumor transformation has …

Cancer is one of the most complex and systemic diseases affecting the health of mankind,
causing major deaths with a significant increase. This pathology is caused by several risk …

Cell death is a fundamental part of life for metazoans. To maintain the balance between cell
proliferation and metabolism of human bodies, a certain number of cells need to be removed …

Long noncoding RNAs (lncRNAs) are known to play a key role in chronic myelocytic
leukemia (CML) development, and we aimed to identify the involvement of the lncRNA HOX …

The regulation of gene expression is fundamental to health and life and is essentially carried
out at the promoter region of the DNA of each gene. Depending on the molecular context …

Epigenetic gene regulation is a major control mechanism of gene expression. Most existing
methods for modeling control mechanisms of gene expression use only a single epigenetic …

In a scenario where eco-sustainability and a reduction in chemotherapeutic drug waste are
certainly a prerogative to safeguard the biosphere, the use of natural products (NPs) …

Cancer diseases are a leading cause of death worldwide. Therefore, it is pivotal to search
for bioactive dietary compounds that can avert tumor development. A diet rich in vegetables …

The worldwide CML incidence expects 100,000 patients every year thus representing a
substantial health burden. A year 2000 is notable year, where Tyrosine kinase inhibitors …

Cancer is a disease related to uncontrolled growth and spreading of affected cells via a
blood torrent. Breast cancer (BC) is a cancer type that originates mainly in milk glands and …