Aptamers are exciting smart molecular probes for specific recognition of disease biomarkers.
A number of strategies have been developed to convert target–aptamer binding into …

Among the various advantages of aptamers over antibodies, remarkable is their ability to
tolerate a large number of chemical modifications within their backbone or at the termini …

Previous evidences reveal that long non-coding RNA (lncRNA) down syndrome critical
region 8 (DSCR8) involves in the progression of multiple cancers. However, the exact …

Nucleic acid aptamers are small three-dimensional structures of oligonucleotides selected to
bind to a target of interest with high affinity and specificity. In vitro, aptamers already compete …

Melanoma, a malignant form of skin cancer, has been swiftly increasing in recent years.
Although there have been significant advancements in clinical treatment underlying a well …

PTK7 (protein tyrosine kinase 7) is an evolutionarily conserved transmembrane receptor
regulating various processes in embryonic development and tissue homeostasis. On a …

Melanoma is one of the most aggressive and deadly skin cancers, and although
histopathological criteria are used for its prognosis, biomarkers are necessary to identify the …

A fluorometric aptamer-based assay was developed for ultrasensitive and selective
determination of the neonicotinoid insecticide acetamiprid. The method is based on the use …

One of the most dangerous cancers is the malignancy related to blood cells such as variety
types of leukemias, lymphomas and multiple myeloma. Early diagnosis of cancers can be …

Aptamers are oligonucleotides that have the characteristic of recognizing a target with high
affinity and specificity. Based on our previous studies, the aptamer probe Sgc8-c-Alexa647 …