Microbubbles in ultrasound-triggered drug and gene delivery

S Hernot, AL Klibanov - Advanced drug delivery reviews, 2008 - Elsevier
Ultrasound contrast agents, in the form of gas-filled microbubbles, are becoming popular in
perfusion monitoring; they are employed as molecular imaging agents. Microbubbles are …

[HTML][HTML] Therapeutic applications of ultrasound

G Ter Haar - Progress in biophysics and molecular biology, 2007 - Elsevier
Therapeutic applications of ultrasound predate its use in imaging. A range of biological
effects can be induced by ultrasound, depending on the exposure levels used. At low levels …

Ultrasonic drug delivery–a general review

WG Pitt, GA Husseini, BJ Staples - Expert opinion on drug delivery, 2004 - Taylor & Francis
Ultrasound has an ever-increasing role in the delivery of therapeutic agents, including
genetic material, protein and chemotherapeutic agents. Cavitating gas bodies, such as …

Therapeutic applications of lipid-coated microbubbles

EC Unger, T Porter, W Culp, R Labell… - Advanced drug delivery …, 2004 - Elsevier
Lipid-coated microbubbles represent a new class of agents with both diagnostic and
therapeutic applications. Microbubbles have low density. Stabilization of microbubbles by …

Non-viral gene delivery methods

W Wang, W Li, N Ma, G Steinhoff - Current pharmaceutical …, 2013 - ingentaconnect.com
Gene delivery has attracted increasing interest as a highly promising therapeutic method to
treat various diseases, including both genetic and acquired disorders. Viral-vectors based …

Cavitation in medicine

CE Brennen - Interface focus, 2015 - royalsocietypublishing.org
We generally think of bubbles as benign and harmless and yet they can manifest the most
remarkable range of physical effects. Some of those effects are the stuff of our everyday …

Micelles and nanoparticles for ultrasonic drug and gene delivery

GA Husseini, WG Pitt - Advanced drug delivery reviews, 2008 - Elsevier
Drug delivery research employing micelles and nanoparticles has expanded in recent years.
Of particular interest is the use of these nanovehicles that deliver high concentrations of …

Physical methods for gene transfer: improving the kinetics of gene delivery into cells

S Mehier-Humbert, RH Guy - Advanced drug delivery reviews, 2005 - Elsevier
One factor critical to successful gene therapy is the development of efficient delivery
systems. Although advances in gene transfer technology, including viral and non-viral …

Use of biomarkers and therapeutic agents with surgical devices

JW Clymer, P Malaviya, DL Korvick, KL Houser… - US Patent …, 2013 - Google Patents
(51) Int. Cl. The same apparatus or anotherapparatus is used to administer A6M
37/00(2006.01) a therapeutic agent based at least in part on collected biom A6 …

Advances in gene delivery systems

K Kamimura, T Suda, G Zhang, D Liu - Pharmaceutical medicine, 2011 - Springer
The transfer of genes into cells, both in vitro and in vivo, is critical for studying gene function
and conducting gene therapy. Methods that utilize viral and nonviral vectors, as well as …