Interpreting the mechanisms and principles that govern gene activity and how these genes
work according to-their cellular distribution in organisms has profound implications for …

Cell stress is inherent to cancer and a key driver of tumorigenesis. Recent studies have
proposed that cell stress promotes tumorigenesis through non-membranous organelles …

Programmed cell death protein 1 (PD-1)/programmed death-ligand 1 (PD-L1)-blockade
immunotherapies have limited efficacy in the treatment of bladder cancer. Here, we show …

INTRODUCTION Cells and tissues are made up of diverse molecular building blocks,
organized with nanoscale precision over extended length scales. Newly developed …

We present a sheathless, microfluidic imaging flow cytometer that incorporates stroboscopic
illumination for blur-free fluorescence detection at ultra-high analytical throughput. The …

Antimitotics are important anticancer agents and include the natural alkaloid prodrug
colchicine (COL). However, a major challenge of using COL as an anticancer drug is its …

Stress granules (SGs) are primarily composed of mRNAs that stall at translation initiation
and usually appear in the cytoplasm under unusual physiological or pathological conditions …

Several solid malignancies trigger lymphangiogenesis, facilitating metastasis. Tumor-
associated lymphatic vessels significantly contribute to the generation of an …

Simple Summary In recent years, immunotherapy has emerged as a pillar in the fight against
cancer. However, the heterogeneity within the tumor microenvironment poses challenges to …

Abstract Programmed Cell Death 1 (PD-1) receptor and its ligands (PD-Ls) are essential to
maintain peripheral immune tolerance and to avoid tissue damage. Consequently, altered …