Co-administration of metformin and/or glibenclamide with losartan reverse NG-nitro-l-arginine-methyl ester-streptozotocin-induced hypertensive diabetes and …

EG Moke, EKI Omogbai, SDE Osagie-Eweka… - Microvascular …, 2023 - Elsevier
Over the years, there have been opinions on whether to reduced blood pressure (BP) to a
different levels in patients with diabetes mellitus. Hence, this study investigated the efficacy …

Pathophysiological mechanisms of type 2 diabetes mellitus and the effects of metformin treatment in adult male albino rats.

IY Ibrahim, FF Ali, EA Abdel-Hakeem… - Minia Journal of …, 2023 - mjmr.journals.ekb.eg
Background: Type 2 diabetes mellitus (T2DM) is a chronic global disease characterized by
serious complications. Evidence has shown that free radicals' formation is involved in the …

Ameliorative Effect of Metformin and Vildagliptin on Rat Model Diabetic Kidney Disease

M Hussein, G Zakaria, A Abdelkhalek… - Zagazig Veterinary …, 2024 - zvjz.journals.ekb.eg
Diabetic kidney disease (DKD) serves as the leading factor in the development of chronic
kidney disease, which Progress to end-stage renal failure. Metformin is the first-line therapy …

Optimizing the therapeutic dose of Leiurus quinquestratus scorpion venom in type-2 diabetic mellitus rats

W Salama, A Saleh, M Mostafa - Biological and Biomedical Journal, 2024 - journals.ekb.eg
Diabetes mellitus (DM) is a common chronic disease. Recently, Leiurus quinquestratus
venom (LQV) showed anti-diabetic effect against type-2 DM (T2-DM). This study aimed to …

Biochemical Effects of High Concentration of Colocasia Esculenta Flour Fed on Streptozotocin-Induced Diabetic Rats

HC Uro-Chukwu, AS Ezekwe… - International …, 2024 - info.classicrepository.com
Background: An endocrine and metabolic disease of the pancreas such as Diabetes Mellitus
(DM), is of Public health dimension responsible for 536.6 million cases in the globe. The …