Nitric oxide (NO) is a small free radical with critical signaling roles in physiology and pathophysiology. The generation of sufficient NO levels to regulate the resistance of the …
Nitric oxide (NO) signalling has pleiotropic roles in biology and a crucial function in cardiovascular homeostasis. Tremendous knowledge has been accumulated on the …
Y Zhao, PM Vanhoutte, SWS Leung - Journal of pharmacological sciences, 2015 - Elsevier
As the first discovered gaseous signaling molecule, nitric oxide (NO) affects a number of cellular processes, including those involving vascular cells. This brief review summarizes …
V Kapil, RS Khambata, DA Jones, K Rathod… - Pharmacological …, 2020 - Elsevier
In contrast to nitric oxide, which has well established and important roles in the regulation of blood flow and thrombosis, neurotransmission, the normal functioning of the genitourinary …
Nitric oxide (NO) is an endogenously produced signaling molecule that regulates blood flow and platelet activation. However, intracellular and intravascular diffusion of NO are limited by …
LH Miller, HC Ackerman, X Su, TE Wellems - Nature medicine, 2013 - nature.com
Plasmodium falciparum malaria, an infectious disease caused by a parasitic protozoan, claims the lives of nearly a million children each year in Africa alone and is a top public …
The inorganic anions nitrate (NO3−) and nitrite (NO2−) were previously thought to be inert end products of endogenous nitric oxide (NO) metabolism. However, recent studies show …
DA Gell - Blood Cells, Molecules, and Diseases, 2018 - Elsevier
Haemoglobin (Hb) is widely known as the iron-containing protein in blood that is essential for O 2 transport in mammals. Less widely recognised is that erythrocyte Hb belongs to a …
E Murphy, C Steenbergen - Physiological reviews, 2008 - journals.physiology.org
Mitochondria play an important role in cell death and cardioprotection. During ischemia, when ATP is progressively depleted, ion pumps cannot function resulting in a rise in calcium …