Inflammatory mechanisms are increasingly recognized as important contributors to the
pathogenesis of neurodegenerative diseases, including Lewy body dementia (LBD). Our …

Population ageing is increasing in prevalence in most developed countries. Ageing is the
decline of functional properties at the cellular, tissue, and organ level. Biochemical changes …

Age-associated changes in the T cell compartment are well described. However, limitations
of current single-modal or bimodal single-cell assays, including flow cytometry, RNA-seq …

Activation of the innate immune system following pattern recognition receptor binding has
emerged as one of the major pathogenic mechanisms in neurodegenerative disease …

Aging is characterized by progressive loss of organ and tissue function, and the immune
system is no exception to that inevitable principle. Of all the age-related changes in the …

Advancements in understanding skin aging mechanisms, which encompass both external
and internal aging processes, have spurred the development of innovative treatments …

(1) Aim: To describe, in a general adult population, the serum N-glycome in relation to age in
men and women, and investigate the association of N-glycome patterns with age-related …

Abstract The Activator Protein 1 (AP-1) transcription factor complex plays a pivotal role in the
regulation of cancer-related genes, influencing cancer cell proliferation, invasion, migration …

Background Energy-adjusted dietary inflammatory index (E-DII) can represent daily
inflammatory dietary components and chronic inflammatory response is an important …

Our traditional medical mindset and healthcare culture are being severely challenged. In the
face of novel infectious diseases, such as Coronavirus 2019 (COVID-19), along with rising …