Biomimetic anisotropic polymeric nanoparticles coated with red blood cell membranes for enhanced circulation and toxin removal

E Ben-Akiva, RA Meyer, H Yu, JT Smith, DM Pardoll… - Science …, 2020 - science.org
The design of next-generation nanobiomaterials requires precise engineering of both
physical properties of the core material and chemical properties of the material's surface to …

Shape matters: Biodegradable anisotropic nanoparticle artificial antigen presenting cells for cancer immunotherapy

E Ben-Akiva, JW Hickey, RA Meyer, A Isser… - Acta biomaterialia, 2023 - Elsevier
Artificial antigen presenting cells are biomimetic particles that recapitulate the signals
presented by natural antigen presenting cells in order to stimulate T cells in an antigen …

Cell‐sized lipid vesicles as artificial antigen‐presenting cells for antigen‐specific T cell activation

JY Chen, S Agrawal, HP Yi, D Vallejo… - Advanced …, 2023 - Wiley Online Library
In this study, efficient T cell activation is demonstrated using cell‐sized artificial antigen‐
presenting cells (aAPCs) with protein‐conjugated bilayer lipid membranes that mimic …

[HTML][HTML] DNA-based artificial dendritic cells for in situ cytotoxic T cell stimulation and immunotherapy

QV Le, J Lee, J Byun, G Shim, YK Oh - Bioactive Materials, 2022 - Elsevier
In immunotherapy, ex vivo stimulation of T cells requires significant resources and effort.
Here, we report artificial dendritic cell-mimicking DNA microflowers (DM) for programming T …

Antigen‐Presenting Hybrid Colloidal Crystal Clusters for Promoting T cells Expansion

X Shou, H Zhang, D Wu, L Zhong, D Ni, T Kong, Y Zhao… - Small, 2021 - Wiley Online Library
T cell based‐immunotherapy has been a powerful strategy to eradicate tumor cells in clinical
trials. Effectively expanding the therapeutic T cells for clinical demand is still a challenge …