Perioperative cardioprotection: general mechanisms and pharmacological approaches

C Torregroza, A Raupach, K Feige… - Anesthesia & …, 2020 - journals.lww.com
Cardioprotection encompasses a variety of strategies protecting the heart against
myocardial injury that occurs during and after inadequate blood supply to the heart during …

Pharmacological conditioning of the heart: an update on experimental developments and clinical implications

S Roth, C Torregroza, K Feige, B Preckel… - International journal of …, 2021 - mdpi.com
The aim of pharmacological conditioning is to protect the heart against myocardial ischemia-
reperfusion (I/R) injury and its consequences. There is extensive literature that reports a …

From traditional pharmacological towards nucleic acid-based therapies for cardiovascular diseases

U Landmesser, W Poller, S Tsimikas… - European heart …, 2020 - academic.oup.com
Nucleic acid-based therapeutics are currently developed at large scale for prevention and
management of cardiovascular diseases (CVDs), since:(i) genetic studies have highlighted …

Long noncoding RNA NEAT1 sponges miR‐495‐3p to enhance myocardial ischemia‐reperfusion injury via MAPK6 activation

M Luo, Q Sun, H Zhao, J Tao… - Journal of Cellular …, 2020 - Wiley Online Library
The biological function of long noncoding RNA NEAT1 has been revealed in a lot of
diseases. Nevertheless, it is still not yet clear whether NEAT1 can modulate the process of …

Gamma-glutamyl transferase-to-platelet ratio as a novel predictor of long-term adverse outcomes in patients after undergoing percutaneous coronary intervention: a …

YY Zheng, TT Wu, Y Chen, XG Hou… - Thrombosis and …, 2019 - thieme-connect.com
Background Gamma-glutamyl transferase (GGT) has been shown to be involved in the
pathogenesis of both coronary artery disease (CAD) and liver disease, and it has been …

[HTML][HTML] Reactive oxygen species related noncoding RNAs as regulators of cardiovascular diseases

Y Dong, W Xu, C Liu, P Liu, P Li… - International journal of …, 2019 - ncbi.nlm.nih.gov
Reactive oxygen species (ROS) are a class of reactive molecules that have been implicated
in a variety of cardiovascular diseases, accompanied by disorder of multiple signaling …

Critical roles of microRNA-141-3p and CHD8 in hypoxia/reoxygenation-induced cardiomyocyte apoptosis

B Yao, X Wan, X Zheng, T Zhong, J Hu, Y Zhou, A Qin… - Cell & Bioscience, 2020 - Springer
Background Cardiovascular diseases are currently the leading cause of death in humans.
The high mortality of cardiac diseases is associated with myocardial ischemia and …

Novel roles of κ-opioid receptor in myocardial ischemia-reperfusion injury

W Zhang, Q Zhang, Y Liu, J Pei, N Feng - PeerJ, 2024 - peerj.com
Acute heart attack is the primary cause of cardiovascular-related death worldwide. A
common treatment is reperfusion of ischemic tissue, which can cause irreversible damage to …

Exploring unconventional risk-factors for cardiovascular diseases: has opioid therapy been overlooked?

O Ogungbe, L Akil, HA Ahmad - International journal of environmental …, 2019 - mdpi.com
Approximately 2150 adults die every day in the US from Cardiovascular Diseases (CVD)
and another 115 deaths are attributed to opioid-related causes. Studies have found …

Breast cancer and anaesthesia: genetic influence

A Raigon Ponferrada, JL Guerrero Orriach… - International Journal of …, 2021 - mdpi.com
Breast cancer is the leading cause of mortality in women. It is a heterogeneous disease with
a high degree of inter-subject variability even in patients with the same type of tumor, with …