De-escalation or abbreviation of dual antiplatelet therapy in acute coronary syndromes and percutaneous coronary intervention: a Consensus Statement from an …

DA Gorog, JL Ferreiro, I Ahrens, J Ako… - Nature Reviews …, 2023 - nature.com
Conventional dual antiplatelet therapy (DAPT) for patients with acute coronary syndromes
undergoing percutaneous coronary intervention comprises aspirin with a potent P2Y …

1-year outcomes of patients undergoing primary angioplasty for myocardial infarction treated with prasugrel versus ticagrelor

Z Motovska, O Hlinomaz, P Kala, M Hromadka… - Journal of the American …, 2018 - jacc.org
Background: Early outcomes of patients in the PRAGUE-18 (Comparison of Prasugrel and
Ticagrelor in the Treatment of Acute Myocardial Infarction) study did not find any significant …

Antithrombotic therapy for patients with chronic coronary syndromes

WAE Parker, RF Storey - Heart, 2021 - heart.bmj.com
Globally, much morbidity and premature mortality arises from coronary artery disease (CAD).
Coronary artery atherothrombosis is the dominant cause of acute coronary syndromes …

Thrombo-inflammation in cardiovascular disease: an expert consensus document from the Third Maastricht Consensus Conference on Thrombosis

E d'Alessandro, C Becker, W Bergmeier… - Thrombosis and …, 2020 - thieme-connect.com
Thrombo-inflammation describes the complex interplay between blood coagulation and
inflammation that plays a critical role in cardiovascular diseases. The third Maastricht …

Real-world comparison of clopidogrel, prasugrel and ticagrelor in patients undergoing primary percutaneous coronary intervention

A Krishnamurthy, C Keeble, M Anderson, K Somers… - Open …, 2019 - openheart.bmj.com
Background There is a paucity of real-world outcome data comparing clopidogrel, prasugrel
and ticagrelor in primary percutaneous coronary intervention (PPCI) for ST-segment …

Pharmacodynamic effects of a 6-hour regimen of enoxaparin in patients undergoing primary percutaneous coronary intervention (PENNY PCI Study)

W Sumaya, WAE Parker, R Fretwell… - Thrombosis and …, 2018 - thieme-connect.com
Delayed onset of action of oral P2Y 12 inhibitors in ST-elevation myocardial infarction
(STEMI) patients may increase the risk of acute stent thrombosis. Available parenteral anti …

Comparative effectiveness and safety of ticagrelor versus prasugrel in patients with acute coronary syndrome: a retrospective cohort analysis

GK Dawwas, E Dietrich, DE Winchester… - … : The Journal of …, 2019 - Wiley Online Library
Study Objective To compare the effectiveness and safety of ticagrelor versus prasugrel in
preventing recurrent cardiovascular disease (CVD) and major bleeding events in patients …

Effects of clopidogrel, prasugrel and ticagrelor on prevention of stent thrombosis in patients underwent percutaneous coronary intervention: A network meta‐analysis

W Chen, C Zhang, J Zhao, X Xu, H Dang… - Clinical …, 2021 - Wiley Online Library
Background Clopidogrel, prasugrel and ticagrelor, acting on platelet P2Y12 receptor, are
commonly used for prevention of stent thrombosis (ST) among patients who underwent …

Secondary prevention of acute coronary events with antiplatelet agents (SPACE-AA): one-year real-world effectiveness and safety cohort study in the French …

P Blin, C Dureau-Pournin, J Benichou, L Bonello… - Atherosclerosis, 2019 - Elsevier
Background and aims We aimed to compare the effectiveness of ticagrelor vs. clopidogrel or
prasugrel on recurrence of acute coronary syndromes (ACS) in real-life conditions, as …

Ticagrelor versus prasugrel for PCI-managed myocardial infarction: the battle of the giants continues

RF Storey - Heart, 2021 - heart.bmj.com
Pharmacodynamic data and large phase III clinical trials have clearly established ticagrelor
and prasugrel as first-line therapies in acute coronary syndrome (ACS) in preference to …