Risk of cancer in bipolar disorder and the potential role of lithium: International collaborative systematic review and meta-analyses

G Anmella, G Fico, M Lotfaliany… - Neuroscience & …, 2021 - Elsevier
We examined bipolar disorder (BD) as a risk factor for developing cancer and the role of
lithium on cancer incidence. We conducted two systematic review and meta-analyses of …

The skeletal-protecting action and mechanisms of action for mood-stabilizing drug lithium chloride: current evidence and future potential research areas

SK Wong, KY Chin, S Ima-Nirwana - Frontiers in Pharmacology, 2020 - frontiersin.org
Lithium, the lightest natural-occurring alkali metal with an atomic number of three, stabilizes
the mood to prevent episodes of acute manic and depression. Multiple lines of evidence …

Association of lithium treatment with the risk of osteoporosis in patients with bipolar disorder

O Köhler-Forsberg, C Rohde, AA Nierenberg… - JAMA …, 2022 - jamanetwork.com
Importance Osteoporosis, a systemic skeletal disorder associated with substantial morbidity
and mortality, may be particularly common among individuals with bipolar disorder. Lithium …

Hair and serum trace element and mineral levels profiles in women with premenopausal and postmenopausal osteoporosis

AV Skalny, TV Korobeinikova, M Aschner… - … Trace Element Research, 2024 - Springer
The objective of the present study was to evaluate serum and hair trace element and mineral
levels in women with osteoporosis, as well as to estimate the impact of menopausal status …

The preconditioning of lithium promotes mesenchymal stem cell-based therapy for the degenerated intervertebral disc via upregulating cellular ROS

Z Zhu, H Xing, R Tang, S Qian, S He, Q Hu… - Stem Cell Research & …, 2021 - Springer
Adipose-derived stem cell (ADSC) is one of the most widely used candidate cell for
intervertebral disc (IVD) degeneration-related disease. However, the poor survival and low …

Association of mental disorders and psychotropic medications with bone texture as measured with trabecular bone score

S Hafizi, LM Lix, D Hans, JM Bolton, WD Leslie - Bone, 2022 - Elsevier
Introduction Mental disorders and psychotropic medications are known to increase the risk
of osteoporosis and fractures. However, current evidence is mostly limited to studies that …

Lithium in Portuguese bottled natural mineral waters—Potential for health benefits?

MO Neves, J Marques, HGM Eggenkamp - International Journal of …, 2020 - mdpi.com
There is increasing epidemiologic and experimental evidence that lithium (Li) exhibits
significant health benefits, even at concentrations lower than the therapeutic oral doses …

Lithium should be borne in mind: Five key reasons

GS Malhi, E Bell, RJ Porter, P Boyce… - Australian & New …, 2020 - journals.sagepub.com
Australian & New Zealand Journal of Psychiatry, 54 (7) somewhat better efficacy in
addressing mania than depression. However, maintenance of the euthymic phase of bipolar …

Toward countering muscle and bone loss with spaceflight: GSK3 as a potential target

RW Baranowski, JL Braun, BL Hockey, JL Yumol… - Iscience, 2023 - cell.com
We examined the effects of∼ 30 days of spaceflight on glycogen synthase kinase 3 (GSK3)
content and inhibitory serine phosphorylation in murine muscle and bone samples from four …

[HTML][HTML] Lithium and the risk of fractures in patients with bipolar disorder: A population-based cohort study

VWS Ng, MTY Leung, WCY Lau, EW Chan, JF Hayes… - Psychiatry …, 2024 - Elsevier
Lithium is considered to be the most effective mood stabilizer for bipolar disorder. Evolving
evidence suggested lithium can also regulate bone metabolism which may reduce the risk of …