A framework for designing delivery systems

W Poon, BR Kingston, B Ouyang, W Ngo… - Nature …, 2020 - nature.com
The delivery of medical agents to a specific diseased tissue or cell is critical for diagnosing
and treating patients. Nanomaterials are promising vehicles to transport agents that include …

Current trends and challenges in cancer management and therapy using designer nanomaterials

PN Navya, A Kaphle, SP Srinivas, SK Bhargava… - Nano convergence, 2019 - Springer
Nanotechnology has the potential to circumvent several drawbacks of conventional
therapeutic formulations. In fact, significant strides have been made towards the application …

Block copolymer micelles in nanomedicine applications

H Cabral, K Miyata, K Osada, K Kataoka - Chemical reviews, 2018 - ACS Publications
Polymeric micelles are demonstrating high potential as nanomedicines capable of
controlling the distribution and function of loaded bioactive agents in the body, effectively …

Form follows function: nanoparticle shape and its implications for nanomedicine

C Kinnear, TL Moore, L Rodriguez-Lorenzo… - Chemical …, 2017 - ACS Publications
This review is a comprehensive description of the past decade of research into
understanding how the geometry and size of nanoparticles affect their interaction with …

The Effect of Nanoparticle Size on In Vivo Pharmacokinetics and Cellular Interaction

N Hoshyar, S Gray, H Han, G Bao - Nanomedicine, 2016 - Taylor & Francis
Nanoparticle-based technologies offer exciting new approaches to disease diagnostics and
therapeutics. To take advantage of unique properties of nanoscale materials and structures …

Cancer nanotechnology: the impact of passive and active targeting in the era of modern cancer biology

N Bertrand, J Wu, X Xu, N Kamaly… - Advanced drug delivery …, 2014 - Elsevier
Cancer nanotherapeutics are progressing at a steady rate; research and development in the
field has experienced an exponential growth since early 2000's. The path to the …

Advanced engineered nanoparticulate platforms to address key biological barriers for delivering chemotherapeutic agents to target sites

J Cao, D Huang, NA Peppas - Advanced drug delivery reviews, 2020 - Elsevier
The widespread development of nanocarriers to deliver chemotherapeutics to specific tumor
sites has been motivated by the lack of selective targeting during chemotherapy inducing …

Multifunctional nanoparticles: cost versus benefit of adding targeting and imaging capabilities

Z Cheng, A Al Zaki, JZ Hui, VR Muzykantov, A Tsourkas - Science, 2012 - science.org
Nanoparticle-based drug delivery systems have been developed to improve the efficacy and
reduce the systemic toxicity of a wide range of drugs. Although clinically approved …

Transporter-guided delivery of nanoparticles to improve drug permeation across cellular barriers and drug exposure to selective cell types

L Kou, YD Bhutia, Q Yao, Z He, J Sun… - Frontiers in …, 2018 - frontiersin.org
Targeted nano-drug delivery systems conjugated with specific ligands to target selective cell-
surface receptors or transporters could enhance the efficacy of drug delivery and therapy …

Review on design strategies and considerations of polysaccharide-based smart drug delivery systems for cancer therapy

Q Meng, S Zhong, L Xu, J Wang, Z Zhang, Y Gao… - Carbohydrate …, 2022 - Elsevier
The unique natural advantages of polysaccharide materials have attracted attention in
biomedical applications. The abundant modifiable functional groups on the polysaccharide …