Retinoic acid (RA), especially all-trans retinoic acid is the most potent natural metabolite of
vitamin A. RA is involved in a variety of biological functions including embryogenesis, cell …

Single-cell patterning represents a key approach to decouple and better understand the role
and mechanisms of individual cells of a given population. In particular, the bottom-up …

Objective: We aimed to develop a method for evaluating developmental changes in the
synchronized activity of human induced pluripotent stem cell (hiPSC)-derived neurons …

Neuroengineering methods can be effectively used in the design of new approaches to treat
central nervous system and brain injury caused by neurotrauma, ischemia, or …

Network bursts or synchronized burst events are a typical activity seen in most in vitro neural
networks. Network bursts arise early in development and as networks mature, activity …

The P19 embryonic stem (ES) cells are derivatives of the inner cell mass of a mouse
blastoderm, are multipotent and can give rise to all three germ layers [1]. They are …

In this study, we developed a new model of neuronal cells plating into a developed neural
network to study functional integration using microfluidic methods. The integration was …

Objective: Neuronal networks are fundamental structures for information processing in the
central nervous system. This processing function is severely impaired by abnormal axonal …

Neural networks in the central nervous system are composed of neurons which interconnect
through their axons. Although computational capacity of axons is of great interest, their small …

Tumor Suppressors and Endodermal Differentiation of P19 Embryonic Stem Cells Page 1 C ell
& Developmental Bio logy ISSN: 2168-9296 Cell & Developmental Biology Kanungo, Cell Dev …