The gastrointestinal tract has recently come to the forefront of multiple research fields. It is
now recognized as a major source of signals modulating food intake, insulin secretion and …

Excess adipose fat accumulation, or obesity, is a growing problem worldwide in terms of
both the rate of incidence and the severity of obesity-associated metabolic disease. Adipose …

Triacylglycerol (TAG) is the most important caloric source with respect to energy
homeostasis in animals. In addition to its evolutionarily conserved importance as an energy …

Organisms adapt to changing environments by adjusting their development, metabolism,
and behavior to improve their chances of survival and reproduction. To achieve such …

Skeletal muscle is a highly vascularized tissue that can secrete proteins called myokines.
These muscle-secreted factors exert biological functions in muscle itself (autocrine effect) or …

Adipose tissue is a dynamic organ, well known for its function in energy storage and
mobilization according to nutrient availability and body needs, in charge of keeping the …

The insulin-like peptide (ILP) and insulin-like growth factor (IGF) signalling pathways play a
crucial role in the regulation of metabolism, growth and development, fecundity, stress …

Mitochondrial dysfunction promotes metabolic stress responses in a cell‐autonomous as
well as organismal manner. The wasting hormone growth differentiation factor 15 (GDF 15) …

The organs and metabolic pathways involved in energy metabolism, and the process of ATP
production from nutrients, are comparable between humans and Drosophila melanogaster …

The control of systemic metabolic homeostasis involves complex inter-tissue programs that
coordinate energy production, storage, and consumption, to maintain organismal fitness …