Single-cell ICP-MS to address the role of trace elements at a cellular level
ABS da Silva, MAZ Arruda - Journal of Trace Elements in Medicine and …, 2023 - Elsevier
The heterogeneity properties shown by cells or unicellular organisms have led to the
development of analytical methods at the single-cell level. In this sense, considering the …
development of analytical methods at the single-cell level. In this sense, considering the …
Review about powerful combinations of advanced and hyphenated sample introduction techniques with inductively coupled plasma-mass spectrometry (ICP-MS) for …
B Michalke - International Journal of Molecular Sciences, 2022 - mdpi.com
Element analysis in clinical or biological samples is important due to the essential role in
clinical diagnostics, drug development, and drug-effect monitoring. Particularly, the specific …
clinical diagnostics, drug development, and drug-effect monitoring. Particularly, the specific …
Advances in mass spectrometry imaging for toxicological analysis and safety evaluation of pharmaceuticals
Y Chen, Y Xie, L Li, Z Wang… - Mass Spectrometry …, 2023 - Wiley Online Library
Safety issues caused by pharmaceuticals have frequently occurred worldwide, posing a
tremendous threat to human health. As an essential part of drug development, the …
tremendous threat to human health. As an essential part of drug development, the …
Uptake of Gadolinium-Based Contrast Agents by Blood Cells During Contrast-Enhanced MRI Examination
N Ruprecht, D Parakkattel, L Hofmann… - Investigative …, 2024 - journals.lww.com
Objectives Gadolinium-based contrast agents (GBCAs) are routinely used in magnetic
resonance imaging (MRI) examinations. However, there is limited knowledge about the …
resonance imaging (MRI) examinations. However, there is limited knowledge about the …
New advancements in cisplatin-based treatments
E Gentilin - International Journal of Molecular Sciences, 2023 - mdpi.com
Cisplatin (cis-diamminedichloroplatinum (II)) is one of the most broadly used
chemotherapies worldwide. Since the unexpected discovery of its antitumor effects, huge …
chemotherapies worldwide. Since the unexpected discovery of its antitumor effects, huge …
Investigation of the impact of L-phenylalanine and L-tyrosine pre-treatment on the uptake of 4-borono-L-phenylalanine in cancerous and normal cells using an …
E Balcer, J Giebułtowicz, M Sochacka, A Ruszczyńska… - Molecules, 2023 - mdpi.com
Boron has gained significant attention in medical research due to its B-10 isotope's high
cross section for the reaction with thermal neutrons, generating ionizing particles that can …
cross section for the reaction with thermal neutrons, generating ionizing particles that can …
1H HR-MAS NMR Based Metabolic Profiling of Lung Cancer Cells with Induced and De-Induced Cisplatin Resistance to Reveal Metabolic Resistance Adaptations
M Vermathen, H von Tengg-Kobligk, MN Hungerbühler… - Molecules, 2021 - mdpi.com
Cisplatin (cisPt) is an important drug that is used against various cancers, including
advanced lung cancer. However, drug resistance is still a major ongoing problem and its …
advanced lung cancer. However, drug resistance is still a major ongoing problem and its …
Optimizing the performance of single-cell ICP-MS/MS for Fe and Zn determination in human umbilical vascular endothelial cells
KN da Silva Leal, ABS da Silva, AZB Aragão… - Microchemical …, 2024 - Elsevier
Inductively coupled plasma-mass spectrometry operated in a single-cell mode (scICP-
MS/MS) has emerged as a technique that allows measurement of metal concentration at the …
MS/MS) has emerged as a technique that allows measurement of metal concentration at the …
Dynamic elementomics of single-cell ICP–MS-derived signals in normal and calcium pump PMCA4-deficient mouse epididymal sperm during capacitation
BL Zhang, ZP Zhang, SM Shi, HJ Shi, PA DeLeon… - Metallomics, 2023 - academic.oup.com
Currently, clinical analysis of male infertility mainly relies on parameters of semen and
sperm cells. However, the high diagnostic failure rates indicate that the current assessment …
sperm cells. However, the high diagnostic failure rates indicate that the current assessment …
Biomedical analysis by ICP-MS: A focus on single cell strategies
M Montes-Bayón, M Corte-Rodríguez… - Comprehensive …, 2022 - Elsevier
Biomedical applications of ICP-MS have increased significantly over the years, not only
related to total elemental analysis but to speciation studies. Lately, the development of …
related to total elemental analysis but to speciation studies. Lately, the development of …