Unlocking hope: Therapeutic advances and approaches in modulating the WNT pathway for neurodegenerative diseases

N Faraji, N Ebadpour, M Abavisani, A Gorji - Molecular Neurobiology, 2024 - Springer
Neurodegenerative diseases (NDs) are conditions characterized by sensory, motor, and
cognitive impairments due to alterations in the structure and function of neurons in the …

[HTML][HTML] Treatments and preventative measures for trauma‐induced heterotopic ossification: A review

JK Juarez, JC Wenke, JC Rivera - Clinical and translational science, 2018 - ncbi.nlm.nih.gov
Heterotopic ossification (HO) is derived from the Greek terms “heteros”(“other”), topos
(“place”), and “ossification,” a Latin-derived term for “to turn to bone.” HO references lamellar …

Anticancer effects of oridonin on colon cancer are mediated via BMP7/p38 MAPK/p53 signaling

RX Liu, Y Ma, XL Hu, WY Ren… - International …, 2018 - spandidos-publications.com
Colon cancer is a prevalent malignancy affecting the gastrointestinal tract. Oridonin (ORI) is
a promising chemotherapeutic drug used in the treatment of colon cancer. In this study, we …

Taste papilla cell differentiation requires the regulation of secretory protein production by ALK3-BMP signaling in the tongue mesenchyme

M Ishan, Z Wang, P Zhao, Y Yao, SL Stice… - …, 2023 - journals.biologists.com
Taste papillae are specialized organs, each of which comprises an epithelial wall hosting
taste buds and a core of mesenchymal tissue. In the present study, we report that during …

A novel variant in the ROR2 gene underlying brachydactyly type B: a case report

J Shao, Y Liu, S Zhao, W Sun, J Zhan, L Cao - BMC pediatrics, 2022 - Springer
Background Brachydactyly type B is an autosomal dominant disorder that is characterized
by hypoplasia of the distal phalanges and nails and can be divided into brachydactyly type …

[HTML][HTML] Deletion of the Dishevelled family of genes disrupts anterior-posterior axis specification and selectively prevents mesoderm differentiation

J Ngo, M Hashimoto, H Hamada… - Developmental …, 2020 - Elsevier
The Dishevelled proteins transduce both canonical Wnt/β-catenin and non-canonical
Wnt/planar cell polarity (PCP) signaling pathways to regulate many key developmental …

[HTML][HTML] WNT5A-Ca2+-CaN-NFAT signalling plays a permissive role during cartilage differentiation in embryonic chick digit development

A Farrera-Hernández, JC Marín-Llera… - Developmental …, 2021 - Elsevier
During digit development, the correct balance of chondrogenic signals ensures the
recruitment of undifferentiated cells into the cartilage lineage or the maintenance of cells at …

Wnt signaling upregulates Teneurin-3 expression via canonical and non-canonical Wnt pathway crosstalk

S Bastías-Candia, M Martínez, JM Zolezzi… - Frontiers in …, 2019 - frontiersin.org
Teneurins (Tens) are a highly conserved family of proteins necessary for cell-cell adhesion.
Tens can be cleaved, and some of their proteolytic products, such as the teneurin c-terminal …

RNA sequencing and gene co-expression network of in vitro matured oocytes and blastocysts of buffalo

PDPB Santana, KC Pinheiro, LCS Pereira… - Animal …, 2024 - SciELO Brasil
In reproductive technologies, uncovering the molecular aspects of oocyte and embryo
competence under different conditions is crucial for refining protocols and enhancing …

Biscarbamate cross-linked low-molecular-weight polyethylenimine for delivering anti-chordin siRNA into human mesenchymal stem cells for improving bone …

C Wang, W Yuan, F Xiao, Y Gan, X Zhao… - Frontiers in …, 2017 - frontiersin.org
Small-interfering RNA (siRNA) provides a rapid solution for drug design and provides new
methods to develop customizable medicines. Polyethyleneimine 25 kDa (PEI25kDa) is an …