Buccal mucosal membrane offers an attractive drug-delivery route to enhance both systemic
and local therapy. This review discusses the benefits and drawbacks of buccal drug delivery …

The buccal route is considered patient friendly due to its non-invasive nature and ease of
administration. Such delivery route has been used as an alternative for the delivery of drugs …

Buccal drug delivery offers a potential non-invasive means of delivering therapeutics to
patients. Despite the promise, the feasibility of transporting proteins and peptides into …

Insulin nanoparticles (NPs) with high loading content have found diverse applications in
different dosage forms. This work aimed to evaluate the impact of freeze-drying and spray …

There is an ongoing global shift in pharmaceutical business models from small molecule
drugs to biologics. This increase in complexity is in response to advancements in our …

Biologic products are large molecules such as proteins, peptides, nucleic acids, etc., which
have already produced many new drugs for clinical use in the last decades. Due to the …

Buccal delivery of small and large molecules is an attractive route of administration that has
been studied extensively over the past few decades. This route bypasses first-pass …

Diabetes mellitus is a metabolic endocrine disease characterized by chronic hyperglycemia
with disturbances in metabolic processes, such as those related to carbohydrates, fat, and …

The main route of administration for drug products is the oral route, yet biologics are initially
developed as injectables due to their limited stability through the gastrointestinal tract and …

ABSTRACT Introduction: According to the European Pharmacopoeia, oromucosal films
comprise mucoadhesive buccal films and orodispersible films. Both oral dosage forms …