Light input pathways to the circadian clock of insects with an emphasis on the fruit fly Drosophila melanogaster
C Helfrich-Förster - Journal of Comparative Physiology A, 2020 - Springer
Light is the most important Zeitgeber for entraining animal activity rhythms to the 24-h day. In
all animals, the eyes are the main visual organs that are not only responsible for motion and …
all animals, the eyes are the main visual organs that are not only responsible for motion and …
Model and non-model insects in chronobiology
K Beer, C Helfrich-Förster - Frontiers in Behavioral Neuroscience, 2020 - frontiersin.org
The fruit fly Drosophila melanogaster is an established model organism in chronobiology,
because genetic manipulation and breeding in the laboratory are easy. The circadian clock …
because genetic manipulation and breeding in the laboratory are easy. The circadian clock …
Synaptic connectome of the Drosophila circadian clock
N Reinhard, A Fukuda, G Manoli, E Derksen… - Nature …, 2024 - nature.com
The circadian clock and its output pathways play a pivotal role in optimizing daily processes.
To obtain insights into how diverse rhythmic physiology and behaviors are orchestrated, we …
To obtain insights into how diverse rhythmic physiology and behaviors are orchestrated, we …
A transcriptomic taxonomy of Drosophila circadian neurons around the clock
Many different functions are regulated by circadian rhythms, including those orchestrated by
discrete clock neurons within animal brains. To comprehensively characterize and assign …
discrete clock neurons within animal brains. To comprehensively characterize and assign …
A circadian output circuit controls sleep-wake arousal in Drosophila
The Drosophila core circadian circuit contains distinct groups of interacting neurons that give
rise to diurnal sleep-wake patterns. Previous work showed that a subset of dorsal neurons 1 …
rise to diurnal sleep-wake patterns. Previous work showed that a subset of dorsal neurons 1 …
Connectomic analysis of the Drosophila lateral neuron clock cells reveals the synaptic basis of functional pacemaker classes
OT Shafer, GJ Gutierrez, K Li, A Mildenhall, D Spira… - Elife, 2022 - elifesciences.org
The circadian clock orchestrates daily changes in physiology and behavior to ensure
internal temporal order and optimal timing across the day. In animals, a central brain clock …
internal temporal order and optimal timing across the day. In animals, a central brain clock …
The Neuronal Circuit of the Dorsal Circadian Clock Neurons in Drosophila melanogaster
N Reinhard, FK Schubert, E Bertolini… - Frontiers in …, 2022 - frontiersin.org
Drosophila's dorsal clock neurons (DNs) consist of four clusters (DN1as, DN1ps, DN2s, and
DN3s) that largely differ in size. While the DN1as and the DN2s encompass only two …
DN3s) that largely differ in size. While the DN1as and the DN2s encompass only two …
A detailed re-examination of the period gene rescue experiments shows that four to six cryptochrome-positive posterior dorsal clock neurons (DN1p) of Drosophila …
M Sekiguchi, N Reinhard, A Fukuda… - Journal of biological …, 2024 - journals.sagepub.com
Animal circadian clocks play a crucial role in regulating behavioral adaptations to daily
environmental changes. The fruit fly Drosophila melanogaster exhibits 2 prominent peaks of …
environmental changes. The fruit fly Drosophila melanogaster exhibits 2 prominent peaks of …
The lateral posterior clock neurons of Drosophila melanogaster express three neuropeptides and have multiple connections within the circadian clock network and …
N Reinhard, E Bertolini, A Saito… - Journal of …, 2022 - Wiley Online Library
Drosophila's lateral posterior neurons (LPNs) belong to a small group of circadian clock
neurons that is so far not characterized in detail. Thanks to a new highly specific split‐Gal4 …
neurons that is so far not characterized in detail. Thanks to a new highly specific split‐Gal4 …
Integration of Circadian Clock Information in the Drosophila Circadian Neuronal Network
Circadian clocks are biochemical time-keeping machines that synchronize animal behavior
and physiology with planetary rhythms. In Drosophila, the core components of the clock …
and physiology with planetary rhythms. In Drosophila, the core components of the clock …