Nanomedicine for Diagnosis and Treatment of Atherosclerosis

J Cheng, H Huang, Y Chen, R Wu - Advanced Science, 2023 - Wiley Online Library
With the changing disease spectrum, atherosclerosis has become increasingly prevalent
worldwide and the associated diseases have emerged as the leading cause of death. Due …

[HTML][HTML] Recent advances of self-assembled nanoparticles in the diagnosis and treatment of atherosclerosis

T Aili, J Zong, Y Zhou, Y Liu, X Yang, B Hu… - Theranostics, 2024 - pmc.ncbi.nlm.nih.gov
Atherosclerosis remains a significant global health challenge, with its related conditions as
the leading cause of death, underscoring the urgent need for enhanced diagnostic and …

[HTML][HTML] MCL attenuates atherosclerosis by suppressing macrophage ferroptosis via targeting KEAP1/NRF2 interaction

X Luo, Y Wang, X Zhu, Y Chen, B Xu, X Bai, X Weng… - Redox biology, 2024 - Elsevier
Background Micheliolide (MCL), which is the active metabolite of parthenolide, has
demonstrated promising clinical application potential. However, the effects and underlying …

Lipid nanoparticles encapsulating curcumin for imaging and stabilization of vulnerable atherosclerotic plaques via phagocytic “eat-me” signals

Z Shi, J Huang, C Chen, X Zhang, Z Ma… - Journal of Controlled …, 2024 - Elsevier
Curcumin potentiates the stabilization of atherosclerotic plaques by polarizing
macrophages, but its non-specific targeting hinders its clinical application. We aim to …

Dual‐Function Nanoscale Coordination Polymer Nanoparticles for Targeted Diagnosis and Therapeutic Delivery in Atherosclerosis

Y Lin, J Liu, SY Chong, HJ Ting, X Tang, L Yang… - Small, 2024 - Wiley Online Library
Atherosclerosis is the primary cause of cardiovascular events such as heart attacks and
strokes. However, current medical practice lacks non‐invasive, reliable approaches for both …

[HTML][HTML] The MEK-ERK-Egr-1 axis and its regulation in cardiovascular disease

LM Khachigian - Vascular Pharmacology, 2023 - Elsevier
Cardiovascular disease (CVD) is the primary cause of morbidity and mortality in the Western
world. Multiple molecular and cellular processes underpinning the pathogenesis of CVD are …

[HTML][HTML] Black phosphorus nanoplatform coated with platelet membrane improves inhibition of atherosclerosis progression through macrophage targeting and …

J Zhang, Z Wang, Y Liao, J Tong, R Gao, Z Zeng, Y Bai… - Acta Biomaterialia, 2025 - Elsevier
Plaque rupture in atherosclerosis (AS) is a major cause of acute cardiovascular events.
Macrophage-induced inflammatory responses and accumulation of excess reactive oxygen …

Innovation of Lipid‐Based Nanoparticles: the Design and Applications in the Cardiovascular Disease Management

Z Gu, T Liu, W Rao, D Li, Q Zhang, J Dai… - Advanced Functional …, 2025 - Wiley Online Library
Cardiovascular diseases (CVDs) represent a prominent cause of global mortality, posing
considerable challenges for traditional therapies due to their limited bioavailability and …

Advances in Research on Marine-Derived Lipid-Lowering Active Substances and Their Molecular Mechanisms

L Liu, Y Chen, B Chen, M Xu, S Liu, Y Su, K Qiao, Z Liu - Nutrients, 2023 - mdpi.com
Hyperlipidemia (HLP) is a metabolic disorder caused by abnormal lipid metabolism.
Recently, the prevalence of HLP caused by poor dietary habits in the population has been …

Oral Lipids/Fatty Acids Supplements and Eczema: What Is Known?

A Cespedes Zablah, P Lio - Dermatitis®, 2025 - liebertpub.com
The pathogenesis of atopic dermatitis (AD) points to skin barrier dysfunction as a critical
piece of the puzzle. Deficiencies in fatty acids and ceramides—key elements of the skin …