Respiratory disorders, especially non-communicable, chronic inflammatory diseases, are
amongst the leading causes of mortality and morbidity worldwide. Respiratory diseases …

Pleural Disease This review discusses the substantial advances that have been made in our
understanding of pleural biology and related pathophysiology, as well as in the …

Malignant pleural effusions are common in patients with cancer. Most malignant pleural
effusions are secondary to metastases to the pleura, most often from lung or breast cancer …

Malignant pleural effusion (MPE) is an exudative effusion with malignant cells. MPE is a
common symptom and accompanying manifestation of metastatic disease. It affects up to …

Background The prevalence of malignant pleural effusion is increasing worldwide, but
prognostic biomarkers to plan treatment and to understand the underlying mechanisms of …

The complex interactions among different immune cells have important functions in the
development of malignant pleural effusion (MPE). Here we perform single-cell RNA …

Background Pleural fluid cytology is an important diagnostic test used for the investigation of
pleural effusions. There is considerable variability in the reported sensitivity for the diagnosis …

Breast cancer (BC) cell lines are useful experimental models to understand cancer biology.
Yet, their relevance to modelling cancer remains unclear. To better understand the tumour …

Malignant pleural effusion (MPE) is a sign of advanced cancer and is associated with
significant symptom burden and mortality. To date, management has been palliative in …

Symptomatic malignant pleural effusion is a common clinical problem. This condition is
associated with very high mortality, with life expectancy ranging from 3 to 12 months. Studies …