Genetically targeted chemical assembly

A Zhang, Y Jiang, KY Loh, Z Bao… - Nature Reviews …, 2024 - nature.com
Cell type-specific interfaces within living animals will be invaluable for achieving
communication with identifiable cells over the long term, enabling applications across many …

In Situ Synthesis and Assembly of Functional Materials and Devices in Living Systems

W Wang, CD Sessler, X Wang, J Liu - Accounts of Chemical …, 2024 - ACS Publications
Conspectus Integrating functional materials and devices with living systems enables novel
methods for recording, manipulating, or augmenting organisms not accessible by traditional …

High titer production of gastrodin enabled by systematic refactoring of yeast genome and an antisense-transcriptional regulation toolkit

Y Gu, Y Jiang, C Li, J Zhu, X Lu, J Ge, M Hu, J Deng… - Metabolic …, 2024 - Elsevier
Gastrodin, a phenolic glycoside, is a prominent component of Gastrodia elata, which is
renowned for its sedative, hypnotic, anticonvulsant, and neuroprotective activities …

Exploring Present and Future Directions in Nano-Enhanced Optoelectronic Neuromodulation

C Yang, Z Cheng, P Li, B Tian - Accounts of Chemical Research, 2024 - ACS Publications
Conspectus Electrical neuromodulation has achieved significant translational
advancements, including the development of deep brain stimulators for managing neural …

Applications of synthetic polymers directed toward living cells

A Zhang, S Zhao, J Tyson, K Deisseroth, Z Bao - Nature Synthesis, 2024 - nature.com
Cells execute remarkable functions using biopolymers synthesized from natural building
blocks. Engineering cells to leverage the vast array of synthesizable abiotic polymers could …

Using Chemistry To Recreate the Complexity of the Extracellular Matrix: Guidelines for Supramolecular Hydrogel–Cell Interactions

L Rijns, MB Baker, PYW Dankers - Journal of the American …, 2024 - ACS Publications
Hydrogels have emerged as a promising class of extracellular matrix (ECM)-mimicking
materials in regenerative medicine. Here, we briefly describe current state-of-the-art of ECM …

生物医用高分子材料细胞膜表面功能化的策略与应用

廖宇思, 梁剑箫, 温转, 蔡明泽, 宋张志, 张薿元… - 高分子学报, 2024 - gfzxb.org
细胞膜是细胞的外层包裹结构, 保护细胞内部免受外界干扰. 通过对细胞膜进行修饰,
引入特定的分子或结构, 可以实现对细胞命运和功能的调控, 从而赋予细胞特殊的功能. 近年来 …

Genetically-encoded photosensitizers enable light-controlled polymerization on living neuronal membranes

A Zhang, CS Kadur, C Ramakrishnan, Z Bao… - bioRxiv, 2022 - biorxiv.org
The ability to record, stimulate, and modify brains of living animals would unlock numerous
research opportunities and create potential clinical interventions, but it is difficult to interface …